Wang TT, Tavera-Mendoza LE, Laperriere D, Libby E, MacLeod NB, Nagai Y, Bourdeau V, Konstorum A, Lallemant B, Zhang R, et al: Large-scale in silico and microarray-based identification of direct 1,25-dihydroxyvitamin D3 target genes. Mol Endocrinol. 2005, 19 (11): 2685-2695. 10.1210/me.2005-0106.
Article
CAS
PubMed
Google Scholar
Ross AC, Institute of Medicine (U. S.). Committee to Review Dietary Reference Intakes for Vitamin D and Calcium: Dietary reference intakes for calcium and vitamin D. 2011, Washington, DC: National Academies Press
Google Scholar
Looker AC, Lacher DA, et al: Vitamin D status: United States, 2001–2006. NCHS Data Brief. 2011, 59: 1-7.
PubMed
Google Scholar
Minino AM: Death in the United States, 2009. NCHS Data Brief. 2011, 1-8. 64
Eisner MD, Anthonisen N, Coultas D, Kuenzli N, Perez-Padilla R, Postma D, Romieu I, Silverman EK, Balmes JR: An official American Thoracic Society public policy statement: Novel risk factors and the global burden of chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2010, 182 (5): 693-718. 10.1164/rccm.200811-1757ST.
Article
PubMed
Google Scholar
Finklea JD, Grossmann RE, Tangpricha V: Vitamin D and chronic lung disease: a review of molecular mechanisms and clinical studies. Adv Nutr. 2011, 2: 244-253. 10.3945/an.111.000398.
Article
CAS
PubMed
PubMed Central
Google Scholar
Black PN, Scragg R: Relationship between serum 25-hydroxyvitamin D and pulmonary function in the third national health and nutrition examination survey. Chest. 2005, 128 (6): 3792-3798. 10.1378/chest.128.6.3792.
Article
CAS
PubMed
Google Scholar
Shaheen SO, Jameson KA, Robinson SM, Boucher BJ, Syddall HE, Aihie Sayer A, Cooper C, Holloway JW, Dennison EM: Relationship of vitamin D status to adult lung function and COPD. Thorax. 2011, 66 (8): 692-698. 10.1136/thx.2010.155234.
Article
PubMed
Google Scholar
Lehouck A, Mathieu C, Carremans C, Baeke F, Verhaegen J, Van Eldere J, Decallonne B, Bouillon R, Decramer M, Janssens W: High doses of vitamin D to reduce exacerbations in chronic obstructive pulmonary disease: a randomized trial. Ann Int Med. 2012, 156 (2): 105-114. 10.7326/0003-4819-156-2-201201170-00004.
Article
PubMed
Google Scholar
Kunisaki KM, Niewoehner DE, Connett JE: Vitamin D levels and risk of acute exacerbations of chronic obstructive pulmonary disease: A prospective cohort study. Am J Respir Crit Care Med. 2012, 185 (3): 286-290. 10.1164/rccm.201109-1644OC.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wittke A, Chang A, Froicu M, Harandi OF, Weaver V, August A, Paulson RF, Cantorna MT: Vitamin D receptor expression by the lung micro-environment is required for maximal induction of lung inflammation. Arch Biochem Biophys. 2007, 460 (2): 306-313. 10.1016/j.abb.2006.12.011.
Article
CAS
PubMed
PubMed Central
Google Scholar
Bosse Y, Maghni K, Hudson TJ: 1alpha,25-dihydroxy-vitamin D3 stimulation of bronchial smooth muscle cells induces autocrine, contractility, and remodeling processes. Physiol Genomics. 2007, 29 (2): 161-168.
Article
CAS
PubMed
Google Scholar
Hansdottir S, Monick MM, Hinde SL, Lovan N, Look DC, Hunninghake GW: Respiratory epithelial cells convert inactive vitamin D to its active form: potential effects on host defense. J Immunol. 2008, 181 (10): 7090-7099.
Article
CAS
PubMed
PubMed Central
Google Scholar
Harvey BG, Heguy A, Leopold PL, Carolan BJ, Ferris B, Crystal RG: Modification of gene expression of the small airway epithelium in response to cigarette smoking. J Mol Med (Berl). 2007, 85 (1): 39-53.
Article
CAS
Google Scholar
Gao C, Tignor N, Salit J, Strulovici-Barel Y, Hackett N, Crystal RG, Mezey JG: HEFT: eQTL analysis of many thousands of expressed genes while simultaneously controlling for hidden factors. Bioinformatics. 2013, in press
Google Scholar
Pruim RJ, Welch RP, Sanna S, Teslovich TM, Chines PS, Gliedt TP, Boehnke M, Abecasis GR, Willer CJ: LocusZoom: regional visualization of genome-wide association scan results. Bioinformatics. 2010, 26 (18): 2336-2337. 10.1093/bioinformatics/btq419.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hancock DB, Eijgelsheim M, Wilk JB, Gharib SA, Loehr LR, Marciante KD, Franceschini N, van Durme YM, Chen TH, Barr RG, et al: Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. Nat Genet. 2010, 42 (1): 45-52. 10.1038/ng.500.
Article
CAS
PubMed
Google Scholar
Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, Crapo R, Enright P, van der Grinten CP, Gustafsson P, et al: Standardisation of spirometry. Eur Respir J. 2005, 26 (2): 319-338. 10.1183/09031936.05.00034805.
Article
CAS
PubMed
Google Scholar
Waterer GW, Wan JY, Kritchevsky SB, Wunderink RG, Satterfield S, Bauer DC, Newman AB, Taaffe DR, Jensen RL, Crapo RO: Airflow limitation is underrecognized in well-functioning older people. J Am Geriatr Soc. 2001, 49 (8): 1032-1038. 10.1046/j.1532-5415.2001.49205.x.
Article
CAS
PubMed
Google Scholar
Mohamed Hoesein FA, Zanen P, Lammers JW: Lower limit of normal or FEV1/FVC < 0.70 in diagnosing COPD: an evidence-based review. Respir Med. 2011, 105 (6): 907-915. 10.1016/j.rmed.2011.01.008.
Article
PubMed
Google Scholar
Artigas MS, Loth DW, Wain LV, Gharib SA, Obeidat M, Tang W, Zhai G, Zhao JH, Smith AV, Huffman JE, et al: Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet. 2011, 43: 1082-1090. 10.1038/ng.941.
Article
CAS
PubMed Central
Google Scholar
Cooper GM, Shendure J: Needles in stacks of needles: finding disease-causal variants in a wealth of genomic data. Nat Rev Genet. 2011, 12 (9): 628-640. 10.1038/nrg3046.
Article
CAS
PubMed
Google Scholar
Storey JD: A direct approach to false discovery rates. J R Statist Soc B. 2002, 64: 479-498. 10.1111/1467-9868.00346.
Article
Google Scholar
Dixon AL, Liang L, Moffatt MF, Chen W, Heath S, Wong KC, Taylor J, Burnett E, Gut I, Farrall M, et al: A genome-wide association study of global gene expression. Nat Genet. 2007, 39 (10): 1202-1207. 10.1038/ng2109.
Article
CAS
PubMed
Google Scholar
Yang Y, Uhlig S: The role of sphingolipids in respiratory disease. Ther Adv Respir Dis. 2011, 5 (5): 325-344. 10.1177/1753465811406772.
Article
CAS
PubMed
Google Scholar
Chi H: Sphingosine-1-phosphate and immune regulation: trafficking and beyond. Trends Pharmacol Sci. 2011, 32 (1): 16-24. 10.1016/j.tips.2010.11.002.
Article
CAS
PubMed
Google Scholar
Mechtcheriakova D, Wlachos A, Sobanov J, Kopp T, Reuschel R, Bornancin F, Cai R, Zemann B, Urtz N, Stingl G, et al: Sphingosine 1-phosphate phosphatase 2 is induced during inflammatory responses. Cell Signal. 2007, 19 (4): 748-760. 10.1016/j.cellsig.2006.09.004.
Article
CAS
PubMed
Google Scholar
Houle F, Poirier A, Dumaresq J, Huot J: DAP kinase mediates the phosphorylation of tropomyosin-1 downstream of the ERK pathway, which regulates the formation of stress fibers in response to oxidative stress. J Cell Sci. 2007, 120 (Pt 20): 3666-3677.
Article
CAS
PubMed
Google Scholar
Mukhopadhyay R, Ray PS, Arif A, Brady AK, Kinter M, Fox PL: DAPK-ZIPK-L13a axis constitutes a negative-feedback module regulating inflammatory gene expression. Mol Cell. 2008, 32 (3): 371-382. 10.1016/j.molcel.2008.09.019.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hao K, Niu T, Xu X, Fang Z: Single-nucleotide polymorphisms of the KCNS3 gene are significantly associated with airway hyperresponsiveness. Hum Genet. 2005, 116 (5): 378-383. 10.1007/s00439-005-1256-5.
Article
CAS
PubMed
Google Scholar
Brutsche MH, Downs SH, Schindler C, Gerbase MW, Schwartz J, Frey M, Russi EW, Ackermann-Liebrich U, Leuenberger P: Bronchial hyperresponsiveness and the development of asthma and COPD in asymptomatic individuals: SAPALDIA cohort study. Thorax. 2006, 61 (8): 671-677. 10.1136/thx.2005.052241.
Article
CAS
PubMed
PubMed Central
Google Scholar
Miyamae T, Marinov AD, Sowders D, Wilson DC, Devlin J, Boudreau R, Robbins P, Hirsch R: Follistatin-like protein-1 is a novel proinflammatory molecule. J Immunol. 2006, 177 (7): 4758-4762.
Article
CAS
PubMed
Google Scholar
Schunemann HJ, Dorn J, Grant BJ, Winkelstein W, Trevisan M: Pulmonary function is a long-term predictor of mortality in the general population: 29-year follow-up of the Buffalo Health Study. Chest. 2000, 118 (3): 656-664. 10.1378/chest.118.3.656.
Article
CAS
PubMed
Google Scholar
Pike JW, Meyer MB, Bishop KA: Regulation of target gene expression by the vitamin D receptor - an update on mechanisms. Rev Endocr Metab Disord. 2012, 13 (1): 45-55. 10.1007/s11154-011-9198-9.
Article
CAS
PubMed
Google Scholar