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Table 5 Associations of SNPs in SGPP2 with risk of prevalent COPD* in African-Americans in the Health, Aging and Body Composition Study

From: Vitamin D-responsive SGPP2 variants associated with lung cell expression and lung function

  

95% Confidence interval

 

SNP**

Odds ratio

Lower

Upper

Nominal P-value

rs4528748

2.63

1.19

5.80

1.64 × 10-02

rs7556867

2.71

1.23

5.99

1.35 × 10-02

rs6758392

2.34

1.07

5.11

3.33 × 10-02

  1. *COPD defined as FEV1 and FEV1/FVC ratio below the Lower Limit of Normal.
  2. *All SNPs modeled as recessive (two copies of the minor allele) to reflect the most significant coding from Table 3, and models adjusted for age, height, smoking, gender, study site, and ancestry principal components.
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BMC Medical Genetics

ISSN: 1471-2350

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