Gartner R, Gasnier BC, Dietrich JW, Krebs B, Angstwurm MW. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations. J Clin Endocrinol Metab. 2002;87(4):1687–91.
Article
CAS
PubMed
Google Scholar
Bonfig W, Gartner R, Schmidt H. Selenium supplementation does not decrease thyroid peroxidase antibody concentration in children and adolescents with autoimmune thyroiditis. TheScientificWorldJOURNAL. 2010;10:990–6.
Article
CAS
PubMed
Google Scholar
Zagrodzki P, Ratajczak R. Selenium supplementation in autoimmune thyroiditis female patient--effects on thyroid and ovarian functions (case study). Biol Trace Elem Res. 2008;126(1–3):76–82.
Article
CAS
PubMed
Google Scholar
Moncayo R, Moncayo H, Kapelari K. Nutritional treatment of incipient thyroid autoimmune disease. Influence of selenium supplementation on thyroid function and morphology in children and young adults. Clin Nutr. 2005;24(4):530–1.
Article
PubMed
Google Scholar
Vrca VB, Skreb F, Cepelak I, Romic Z, Mayer L. Supplementation with antioxidants in the treatment of Graves’ disease; the effect on glutathione peroxidase activity and concentration of selenium. Clin Chim Acta. 2004;341(1–2):55–63.
Article
CAS
PubMed
Google Scholar
Calissendorff J, Mikulski E, Larsen EH, Moller M. A prospective investigation of Graves’ disease and selenium: thyroid hormones, auto-antibodies and self-rated symptoms. Eur Thyroid J. 2015;4(2):93–8.
Article
CAS
PubMed
PubMed Central
Google Scholar
Duntas LH, Mantzou E, Koutras DA. Effects of a six month treatment with selenomethionine in patients with autoimmune thyroiditis. Eur J Endocrinol. 2003;148(4):389–93.
Article
CAS
PubMed
Google Scholar
Turker O, Kumanlioglu K, Karapolat I, Dogan I. Selenium treatment in autoimmune thyroiditis: 9-month follow-up with variable doses. J Endocrinol. 2006;190(1):151–6.
Article
CAS
PubMed
Google Scholar
Nacamulli D, Mian C, Petricca D, Lazzarotto F, Barollo S, Pozza D, Masiero S, Faggian D, Plebani M, Girelli ME, et al. Influence of physiological dietary selenium supplementation on the natural course of autoimmune thyroiditis. Clin Endocrinol. 2010;73(4):535–9.
CAS
Google Scholar
Bacic Vrca V, Skreb F, Cepelak I, Mayer L. Supplementation with antioxidants in the treatment of Graves’ disease: the effect on the extracellular antioxidative parameters. Acta Pharma. 2004;54(2):79–89.
Google Scholar
Karanikas G, Schuetz M, Kontur S, Duan H, Kommata S, Schoen R, Antoni A, Kletter K, Dudczak R, Willheim M. No immunological benefit of selenium in consecutive patients with autoimmune thyroiditis. Thyroid. 2008;18(1):7–12.
Article
CAS
PubMed
Google Scholar
Marcocci C, Kahaly GJ, Krassas GE, Bartalena L, Prummel M, Stahl M, Altea MA, Nardi M, Pitz S, Boboridis K, et al. Selenium and the course of mild Graves’ orbitopathy. N Engl J Med. 2011;364(20):1920–31.
Article
CAS
PubMed
Google Scholar
Hardy-Weinberg equilibrium. http://ihg.gsf.de/cgi-bin/hw/hwa1.pl. Accessed 28 Apr 2017.
Santos LR, Duraes C, Mendes A, Prazeres H, Alvelos MI, Moreira CS, Canedo P, Esteves C, Neves C, Carvalho D, et al. A polymorphism in the promoter region of the selenoprotein S gene (SEPS1) contributes to Hashimoto’s thyroiditis susceptibility. J Clin Endocrinol Metab. 2014;99(4):E719–723.
Article
CAS
PubMed
Google Scholar
Dreher I, Jakobs TC, Kohrle J. Cloning and characterization of the human selenoprotein P promoter. Response of selenoprotein P expression to cytokines in liver cells. J Biol Chem. 1997;272(46):29364–71.
Article
CAS
PubMed
Google Scholar
Mostert V, Dreher I, Kohrle J, Wolff S, Abel J. Modulation of selenoprotein P expression by TGF-beta (1) is mediated by Smad proteins. BioFactors. 2001;14(1–4):135–42.
Article
CAS
PubMed
Google Scholar
Burk RF, Hill KE. Selenoprotein P: an extracellular protein with unique physical characteristics and a role in selenium homeostasis. Annu Rev Nutr. 2005;25:215–35.
Article
CAS
PubMed
Google Scholar
Kabuyama Y, Oshima K, Kitamura T, Homma M, Yamaki J, Munakata M, Homma Y. Involvement of selenoprotein P in the regulation of redox balance and myofibroblast viability in idiopathic pulmonary fibrosis. Genes Cells. 2007;12(11):1235–44.
Article
CAS
PubMed
Google Scholar
Peters U, Chatterjee N, Hayes RB, Schoen RE, Wang Y, Chanock SJ, Foster CB. Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma. Cancer Epidemiol Biomark Prev. 2008;17(5):1144–54.
Article
CAS
Google Scholar
Strauss E, Oszkinis G, Staniszewski R. SEPP1 gene variants and abdominal aortic aneurysm: gene association in relation to metabolic risk factors and peripheral arterial disease coexistence. Sci Rep. 2014;4:7061.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hellwege JN, Palmer ND, Ziegler JT, Langefeld CD, Lorenzo C, Norris JM, Takamura T, Bowden DW. Genetic variants in selenoprotein P plasma 1 gene (SEPP1) are associated with fasting insulin and first phase insulin response in Hispanics. Gene. 2014;534(1):33–9.
Article
CAS
PubMed
Google Scholar
Steinbrecher A, Meplan C, Hesketh J, Schomburg L, Endermann T, Jansen E, Akesson B, Rohrmann S, Linseisen J. Effects of selenium status and polymorphisms in selenoprotein genes on prostate cancer risk in a prospective study of European men. Cancer Epidemiol Biomarkers Prev. 2010;19(11):2958–68.
Article
CAS
PubMed
Google Scholar
Meplan C, Hughes DJ, Pardini B, Naccarati A, Soucek P, Vodickova L, Hlavata I, Vrana D, Vodicka P, Hesketh JE. Genetic variants in selenoprotein genes increase risk of colorectal cancer. Carcinogenesis. 2010;31(6):1074–9.
Article
CAS
PubMed
Google Scholar
Pellatt AJ, Wolff RK, John EM, Torres-Mejia G, Hines LM, Baumgartner KB, Giuliano AR, Lundgreen A, Slattery ML. SEPP1 influences breast cancer risk among women with greater native american ancestry: the breast cancer health disparities study. PLoS One. 2013;8(11):e80554.
Article
PubMed
PubMed Central
Google Scholar
Brigelius-Flohe R. Tissue-specific functions of individual glutathione peroxidases. Free Radic Biol Med. 1999;27(9–10):951–65.
Article
CAS
PubMed
Google Scholar
Villette S, Kyle JA, Brown KM, Pickard K, Milne JS, Nicol F, Arthur JR, Hesketh JE. A novel single nucleotide polymorphism in the 3′ untranslated region of human glutathione peroxidase 4 influences lipoxygenase metabolism. Blood Cells Mol Dis. 2002;29(2):174–8.
Article
PubMed
Google Scholar
Meplan C, Crosley LK, Nicol F, Horgan GW, Mathers JC, Arthur JR, Hesketh JE. Functional effects of a common single-nucleotide polymorphism (GPX4c718t) in the glutathione peroxidase 4 gene: interaction with sex. Am J Clin Nutr. 2008;87(4):1019–27.
CAS
PubMed
Google Scholar
Gautrey H, Nicol F, Sneddon AA, Hall J, Hesketh J. A T/C polymorphism in the GPX4 3′UTR affects the selenoprotein expression pattern and cell viability in transfected Caco-2 cells. Biochim Biophys Acta. 2011;1810(6):584–91.
PubMed
Google Scholar
Udler M, Maia AT, Cebrian A, Brown C, Greenberg D, Shah M, Caldas C, Dunning A, Easton D, Ponder B, et al. Common germline genetic variation in antioxidant defense genes and survival after diagnosis of breast cancer. J Clin Oncol Off J Am Soc Clin Oncol. 2007;25(21):3015–23.
Article
CAS
Google Scholar
Polonikov AV, Vialykh EK, Churnosov MI, Illig T, Freidin MB, Vasil’eva OV, Bushueva OY, Ryzhaeva VN, Bulgakova IV, Solodilova MA. The C718T polymorphism in the 3′-untranslated region of glutathione peroxidase-4 gene is a predictor of cerebral stroke in patients with essential hypertension. Hypertens Res. 2012;35(5):507–12.
Article
CAS
PubMed
Google Scholar
Van Blarigan EL, Ma J, Kenfield SA, Stampfer MJ, Sesso HD, Giovannucci EL, Witte JS, Erdman Jr JW, Chan JM, Penney KL. Plasma antioxidants, genetic variation in SOD2, CAT, GPX1, GPX4, and prostate cancer survival. Cancer Epidemiol Biomarkers Prev. 2014;23(6):1037–46.
Article
PubMed
PubMed Central
Google Scholar
Ye Y, Shibata Y, Yun C, Ron D, Rapoport TA. A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol. Nature. 2004;429(6994):841–7.
Article
CAS
PubMed
Google Scholar
Curran JE, Jowett JB, Elliott KS, Gao Y, Gluschenko K, Wang J, Abel Azim DM, Cai G, Mahaney MC, Comuzzie AG, et al. Genetic variation in selenoprotein S influences inflammatory response. Nat Genet. 2005;37(11):1234–41.
Article
CAS
PubMed
Google Scholar
Suzuki Y, Schmitt MJ. Redox diversity in ERAD-mediated protein retrotranslocation from the endoplasmic reticulum: a complex puzzle. Biol Chem. 2015;396(5):539–54.
Article
CAS
PubMed
Google Scholar
Wang Y, Yang X, Zheng Y, Wu ZH, Zhang XA, Li QP, He XY, Wang CZ, Feng ZC. The SEPS1 G-105A polymorphism is associated with risk of spontaneous preterm birth in a Chinese population. PLoS One. 2013;8(6):e65657.
Article
CAS
PubMed
PubMed Central
Google Scholar