Table 3 Allele and genotype frequencies in AITD patients and controls

Sepp1

rs6865453

A

1338 (74.5)

983 (72.8)

0.307

0.918 (0.779–1.081)

514 (74.1)

0.813

0.975 (0.791–1.201)

C

458 (25.5)

367 (27.2)

180 (25.9)

AA

491 (54.7)

354 (52.4)

0.403

0.918 (0.751–1.122)

184 (53.03)

0.605

0.936 (0.727–1.203)

AC + CC

407 (45.3)

321 (47.6)

163 (47.0)

GPX4

rs713041

C

1031 (57.4)

751 (55.6)

0.329

0.932 (0.809–1.073)

390 (56.2)

0.739

0.970 (0.810–1.160)

T

765 (42.6)

599 (44.37)

304 (43.8)

CC

300 (33.4)

213 (31.6)

0.418

0.915 (0.739–1.133)

105 (30.3)

0.370

0.883 (0.674–1.158)

CT + TT

598 (66.6)

462 (68.5)

242 (69.7)

rs2074451

G

1004 (56.0)

738 (55.2)

0.698

0.972 (0.843–1.120)

375 (54.66)

0.713

0.966 (0.806–1.158)

T

790 (44.0)

598 (44.8)

311 (45.3)

GG

292 (31.4)

207 (31.0)

0.833

0.977 (0.786–1.213)

96 (27.99)

0.343

0.874 (0.662–1.154)

GT + TT

615 (68.6)

451 (69.0)

247 (72.0)

rs3746165

C

1019 (56.7)

738 (54. 7)

0.259

0.921 (0.798)–1.062)

384 (55.33)

0.625

0.955 (0.796–1.146)

T

777 (43.3)

612 (45.3)

310 (44.7)

CC

287 (32.0)

203 (30.1)

0.416

0.914 (0.736–1.135)

98 (28.24)

0.272

0.857 (0.650–1.129)

CT + TT

611 (68.0)

472 (70.0)

249 (71.8)

SEPS1

rs28665122

C

1688 (93.5)

1267 (94.4)

0.297

1.168 (0.872–1.566)

668 (95.16)

0.148

1.325 (0.904–1.943)

T

118 (6.5)

75 (5.6)

34 (4.8)

CC

793 (87.8)

598 (89.1)

0.432

1.134 (0.828–1.554)

320 (91.2)

0.104

1.420 (0.930–21.67)

CT + TT

110 (12.2)

73 (10.9)

31 (8.8)

rs7178239

G

802 (45.6)

620 (46.9)

0.496

1.051 (0.910–1.214)

291 (42.4)

0.167

0.881 (0.735–1.054)

C

958 (54.4)

702 (53.1)

395 (57.6)

GG

180 (20.5)

145 (21.9)

0.514

1.085 (0.848–1.389)

63 (18.4)

0.370

0.863 (0.625–1.190)

CG + CC

700 (79.6)

516 (78.1)

280 (81.6)