Somogyi AA, Barratt DT, Coller JK: Pharmacogenetics of opioids. Clin Pharmacol Ther. 2007, 81: 429-444. 10.1038/sj.clpt.6100095.
Article
CAS
PubMed
Google Scholar
Aubrun F, Langeron O, Quesnel C, Coriat P, Riou B: Relationships between measurement of pain using visual analog score and morphine requirements during postoperative intravenous morphine titration. Anesthesiology. 2003, 98: 1415-1421. 10.1097/00000542-200306000-00017.
Article
CAS
PubMed
Google Scholar
Ashby M, Fleming B, Wood M, Somogyi A: Plasma morphine and glucuronide (M3G and M6G) concentrations in hospice inpatients. J Pain Symptom Manage. 1997, 14: 157-167. 10.1016/S0885-3924(97)00020-1.
Article
CAS
PubMed
Google Scholar
Bond C, LaForge KS, Tian M, Melia D, Zhang S, Borg L, Gong J, Schluger J, Strong JA, Leal SM, Tischfield JA, Kreek MJ, Yu L: Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction. Proc Natl Acad Sci USA. 1998, 95: 9608-9613. 10.1073/pnas.95.16.9608.
Article
CAS
PubMed
PubMed Central
Google Scholar
Conne B, Stutz A, Vassalli JD: The 3' untranslated region of messenger RNA: A molecular 'hotspot' for pathology?. Nat Med. 2000, 6: 637-641. 10.1038/76211.
Article
CAS
PubMed
Google Scholar
Hoehe MR, Kopke K, Wendel B, Rohde K, Flachmeier C, Kidd KK, Berrettini WH, Church GM: Sequence variability and candidate gene analysis in complex disease: association of mu opioid receptor gene variation with substance dependence. Hum Mol Genet. 2000, 9: 2895-2908. 10.1093/hmg/9.19.2895.
Article
CAS
PubMed
Google Scholar
Ide S, Kobayashi H, Tanaka K, Ujike H, Sekine Y, Ozaki N, Inada T, Harano M, Komiyama T, Yamada M, Iyo M, Ikeda K, Sora I: Gene polymorphisms of the mu opioid receptor in methamphetamine abusers. Ann N Y Acad Sci. 2004, 1025: 316-324. 10.1196/annals.1316.039.
Article
CAS
PubMed
Google Scholar
Ikeda K, Ide S, Han W, Hayashida M, Uhl GR, Sora I: How individual sensitivity to opiates can be predicted by gene analyses. Trends Pharmacol Sci. 2005, 26: 311-317. 10.1016/j.tips.2005.04.001.
Article
CAS
PubMed
Google Scholar
Lotsch J, Geisslinger G: Are mu-opioid receptor polymorphisms important for clinical opioid therapy?. Trends Mol Med. 2005, 11: 82-89. 10.1016/j.molmed.2004.12.006.
Article
PubMed
Google Scholar
Lotsch J, Geisslinger G: Relevance of frequent mu-opioid receptor polymorphisms for opioid activity in healthy volunteers. Pharmacogenomics J. 2006, 6: 200-210. 10.1038/sj.tpj.6500362.
Article
CAS
PubMed
Google Scholar
Wang JB, Johnson PS, Persico AM, Hawkins AL, Griffin CA, Uhl GR: Human mu opiate receptor. cDNA and genomic clones, pharmacologic characterization and chromosomal assignment. FEBS Lett. 1994, 338: 217-222. 10.1016/0014-5793(94)80368-4.
Article
CAS
PubMed
Google Scholar
Zhang Y, Wang D, Johnson AD, Papp AC, Sadee W: Allelic expression imbalance of human mu opioid receptor (OPRM1) caused by variant A118G. J Biol Chem. 2005, 280: 32618-32624. 10.1074/jbc.M504942200.
Article
CAS
PubMed
Google Scholar
Lotsch J, Skarke C, Grosch S, Darimont J, Schmidt H, Geisslinger G: The polymorphism A118G of the human mu-opioid receptor gene decreases the pupil constrictory effect of morphine-6-glucuronide but not that of morphine. Pharmacogenetics. 2002, 12: 3-9. 10.1097/00008571-200201000-00002.
Article
CAS
PubMed
Google Scholar
Lotsch J, Zimmermann M, Darimont J, Marx C, Dudziak R, Skarke C, Geisslinger G: Does the A118G polymorphism at the mu-opioid receptor gene protect against morphine-6-glucuronide toxicity?. Anesthesiology. 2002, 97: 814-819. 10.1097/00000542-200210000-00011.
Article
PubMed
Google Scholar
Skarke C, Darimont J, Schmidt H, Geisslinger G, Lotsch J: Analgesic effects of morphine and morphine-6-glucuronide in a transcutaneous electrical pain model in healthy volunteers. Clin Pharmacol Ther. 2003, 73: 107-121. 10.1067/mcp.2003.5.
Article
CAS
PubMed
Google Scholar
Romberg R, Olofsen E, Sarton E, den HJ, Taschner PE, Dahan A: Pharmacokinetic-pharmacodynamic modeling of morphine-6-glucuronide-induced analgesia in healthy volunteers: absence of sex differences. Anesthesiology. 2004, 100: 120-133. 10.1097/00000542-200401000-00021.
Article
CAS
PubMed
Google Scholar
Romberg RR, Olofsen E, Bijl H, Taschner PE, Teppema LJ, Sarton EY, van Kleef JW, Dahan A: Polymorphism of mu-opioid receptor gene (OPRM1:c.118A>G) does not protect against opioid-induced respiratory depression despite reduced analgesic response. Anesthesiology. 2005, 102: 522-530. 10.1097/00000542-200503000-00008.
Article
CAS
PubMed
Google Scholar
Oertel BG, Schmidt R, Schneider A, Geisslinger G, Lotsch J: The mu-opioid receptor gene polymorphism 118A>G depletes alfentanil-induced analgesia and protects against respiratory depression in homozygous carriers. Pharmacogenet Genomics. 2006, 16: 625-636.
Article
CAS
PubMed
Google Scholar
Lotsch J, Skarke C, Wieting J, Oertel BG, Schmidt H, Brockmoller J, Geisslinger G: Modulation of the central nervous effects of levomethadone by genetic polymorphisms potentially affecting its metabolism, distribution, and drug action. Clin Pharmacol Ther. 2006, 79: 72-89. 10.1016/j.clpt.2005.09.010.
Article
PubMed
Google Scholar
Klepstad P, Rakvag TT, Kaasa S, Holthe M, Dale O, Borchgrevink PC, Baar C, Vikan T, Krokan HE, Skorpen F: The 118 A > G polymorphism in the human mu-opioid receptor gene may increase morphine requirements in patients with pain caused by malignant disease. Acta Anaesthesiol Scand. 2004, 48: 1232-1239. 10.1111/j.1399-6576.2004.00517.x.
Article
CAS
PubMed
Google Scholar
Coulbault L, Beaussier M, Verstuyft C, Weickmans H, Dubert L, Tregouet D, Descot C, Parc Y, Lienhart A, Jaillon P, Becquemont L: Environmental and genetic factors associated with morphine response in the postoperative period. Clin Pharmacol Ther. 2006, 79: 316-324. 10.1016/j.clpt.2006.01.007.
Article
CAS
PubMed
Google Scholar
Janicki PK, Schuler G, Francis D, Bohr A, Gordin V, Jarzembowski T, Ruiz-Velasco V, Mets B: A genetic association study of the functional A118G polymorphism of the human mu-opioid receptor gene in patients with acute and chronic pain. Anesth Analg. 2006, 103: 1011-1017. 10.1213/01.ane.0000231634.20341.88.
Article
CAS
PubMed
Google Scholar
Herz A: Endogenous opioid systems and alcohol addiction. Psychopharmacology (Berl). 1997, 129: 99-111. 10.1007/s002130050169.
Article
CAS
Google Scholar
Kreek MJ: Opioid receptors: some perspectives from early studies of their role in normal physiology, stress responsivity, and in specific addictive diseases. Neurochem Res. 1996, 21: 1469-1488. 10.1007/BF02532387.
Article
CAS
PubMed
Google Scholar
Anton RF, Moak DH, Waid LR, Latham PK, Malcolm RJ, Dias JK: Naltrexone and cognitive behavioral therapy for the treatment of outpatient alcoholics: results of a placebo-controlled trial. Am J Psychiatry. 1999, 156: 1758-1764.
CAS
PubMed
Google Scholar
Anton RF, O'Malley SS, Ciraulo DA, Cisler RA, Couper D, Donovan DM, Gastfriend DR, Hosking JD, Johnson BA, LoCastro JS, Longabaugh R, Mason BJ, Mattson ME, Miller WR, Pettinati HM, Randall CL, Swift R, Weiss RD, Williams LD, Zweben A: Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial. JAMA. 2006, 295: 2003-2017. 10.1001/jama.295.17.2003.
Article
CAS
PubMed
Google Scholar
Balldin J, Berglund M, Borg S, Mansson M, Bendtsen P, Franck J, Gustafsson L, Halldin J, Nilsson LH, Stolt G, Willander A: A 6-month controlled naltrexone study: combined effect with cognitive behavioral therapy in outpatient treatment of alcohol dependence. Alcohol Clin Exp Res. 2003, 27: 1142-1149. 10.1097/01.ALC.0000075548.83053.A9.
Article
CAS
PubMed
Google Scholar
Kiefer F, Jahn H, Tarnaske T, Helwig H, Briken P, Holzbach R, Kampf P, Stracke R, Baehr M, Naber D, Wiedemann K: Comparing and combining naltrexone and acamprosate in relapse prevention of alcoholism: a double-blind, placebo-controlled study. Arch Gen Psychiatry. 2003, 60: 92-99.
Article
CAS
PubMed
Google Scholar
Monti PM, Rohsenow DJ, Swift RM, Gulliver SB, Colby SM, Mueller TI, Brown RA, Gordon A, Abrams DB, Niaura RS, Asher MK: Naltrexone and cue exposure with coping and communication skills training for alcoholics: treatment process and 1-year outcomes. Alcohol Clin Exp Res. 2001, 25: 1634-1647. 10.1111/j.1530-0277.2001.tb02170.x.
Article
CAS
PubMed
Google Scholar
O'Malley SS, Jaffe AJ, Chang G, Schottenfeld RS, Meyer RE, Rounsaville B: Naltrexone and coping skills therapy for alcohol dependence. A controlled study. Arch Gen Psychiatry. 1992, 49: 881-887.
Article
PubMed
Google Scholar
Volpicelli JR, Alterman AI, Hayashida M, O'Brien CP: Naltrexone in the treatment of alcohol dependence. Arch Gen Psychiatry. 1992, 49: 876-880.
Article
CAS
PubMed
Google Scholar
Oslin DW, Berrettini W, Kranzler HR, Pettinati H, Gelernter J, Volpicelli JR, O'Brien CP: A functional polymorphism of the mu-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients. Neuropsychopharmacology. 2003, 28: 1546-1552. 10.1038/sj.npp.1300219.
Article
CAS
PubMed
Google Scholar
Gelernter J, Gueorguieva R, Kranzler HR, Zhang H, Cramer J, Rosenheck R, Krystal JH: Opioid receptor gene (OPRM1, OPRK1, and OPRD1) variants and response to naltrexone treatment for alcohol dependence: results from the VA Cooperative Study. Alcohol Clin Exp Res. 2007, 31: 555-563.
CAS
PubMed
Google Scholar
Anton RF, Oroszi G, O'Malley S, Couper D, Swift R, Pettinati H, Goldman D: An evaluation of mu-opioid receptor (OPRM1) as a predictor of naltrexone response in the treatment of alcohol dependence: results from the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence (COMBINE) study. Arch Gen Psychiatry. 2008, 65: 135-144. 10.1001/archpsyc.65.2.135.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hernandez-Avila CA, Wand G, Luo X, Gelernter J, Kranzler HR: Association between the cortisol response to opioid blockade and the Asn40Asp polymorphism at the mu-opioid receptor locus (OPRM1). Am J Med Genet B Neuropsychiatr Genet. 2003, 118: 60-65. 10.1002/ajmg.b.10054.
Article
Google Scholar
Wand GS, McCaul M, Yang X, Reynolds J, Gotjen D, Lee S, Ali A: The mu-opioid receptor gene polymorphism (A118G) alters HPA axis activation induced by opioid receptor blockade. Neuropsychopharmacology. 2002, 26: 106-114. 10.1016/S0893-133X(01)00294-9.
Article
CAS
PubMed
Google Scholar
Arias A, Feinn R, Kranzler HR: Association of an Asn40Asp (A118G) polymorphism in the mu-opioid receptor gene with substance dependence: a meta-analysis. Drug Alcohol Depend. 2006, 83: 262-268. 10.1016/j.drugalcdep.2005.11.024.
Article
CAS
PubMed
Google Scholar
Slutske WS, True WR, Scherrer JF, Heath AC, Bucholz KK, Eisen SA, Goldberg J, Lyons MJ, Tsuang MT: The heritability of alcoholism symptoms: "indicators of genetic and environmental influence in alcohol-dependent individuals" revisited. Alcohol Clin Exp Res. 1999, 23: 759-769.
CAS
PubMed
Google Scholar
Town T, Schinka J, Tan J, Mullan M: The opioid receptor system and alcoholism: a genetic perspective. Eur J Pharmacol. 2000, 410: 243-248. 10.1016/S0014-2999(00)00818-9.
Article
CAS
PubMed
Google Scholar
Schuckit MA: A clinical model of genetic influences in alcohol dependence. J Stud Alcohol. 1994, 55: 5-17.
Article
CAS
PubMed
Google Scholar
Wilhelmsen KC, Schuckit M, Smith TL, Lee JV, Segall SK, Feiler HS, Kalmijn J: The search for genes related to a low-level response to alcohol determined by alcohol challenges. Alcohol Clin Exp Res. 2003, 27: 1041-1047. 10.1097/01.ALC.0000075551.02714.63.
Article
CAS
PubMed
Google Scholar
Schuckit MA: Subjective responses to alcohol in sons of alcoholics and control subjects. Arch Gen Psychiatry. 1984, 41: 879-884.
Article
CAS
PubMed
Google Scholar
Moss HB, Yao JK, Maddock JM: Responses by sons of alcoholic fathers to alcoholic and placebo drinks: perceived mood, intoxication, and plasma prolactin. Alcohol Clin Exp Res. 1989, 13: 252-257. 10.1111/j.1530-0277.1989.tb00322.x.
Article
CAS
PubMed
Google Scholar
O'Malley SS, Maisto SA: Effects of family drinking history and expectancies on responses to alcohol in men. J Stud Alcohol. 1985, 46: 289-297.
Article
PubMed
Google Scholar
Pollock VE, Teasdale TW, Gabrielli WF, Knop J: Subjective and objective measures of response to alcohol among young men at risk for alcoholism. J Stud Alcohol. 1986, 47: 297-304.
Article
CAS
PubMed
Google Scholar
Savoie TM, Emory EK, Moody-Thomas S: Acute alcohol intoxication in socially drinking female and male offspring of alcoholic fathers. J Stud Alcohol. 1988, 49: 430-435.
Article
CAS
PubMed
Google Scholar
Newlin DB, Thomson JB: Alcohol challenge with sons of alcoholics: a critical review and analysis. Psychol Bull. 1990, 108: 383-402. 10.1037/0033-2909.108.3.383.
Article
CAS
PubMed
Google Scholar
Pollock VE: Meta-analysis of subjective sensitivity to alcohol in sons of alcoholics. Am J Psychiatry. 1992, 149: 1534-1538.
Article
CAS
PubMed
Google Scholar
Schuckit MA, Smith TL: An 8-year follow-up of 450 sons of alcoholic and control subjects. Arch Gen Psychiatry. 1996, 53: 202-210.
Article
CAS
PubMed
Google Scholar
Wall TL, Ehlers CL: Acute effects of alcohol on P300 in Asians with different ALDH2 genotypes. Alcohol Clin Exp Res. 1995, 19: 617-622. 10.1111/j.1530-0277.1995.tb01557.x.
Article
CAS
PubMed
Google Scholar
Wall TL, Thomasson HR, Schuckit MA, Ehlers CL: Subjective feelings of alcohol intoxication in Asians with genetic variations of ALDH2 alleles. Alcohol Clin Exp Res. 1992, 16: 991-995. 10.1111/j.1530-0277.1992.tb01907.x.
Article
CAS
PubMed
Google Scholar
Wall TL, Gallen CC, Ehlers CL: Effects of alcohol on the EEG in Asian men with genetic variations of ALDH2. Biol Psychiatry. 1993, 34: 91-99. 10.1016/0006-3223(93)90261-B.
Article
CAS
PubMed
Google Scholar
Wall TL, Nemeroff CB, Ritchie JC, Ehlers CL: Cortisol responses following placebo and alcohol in Asians with different ALDH2 genotypes. J Stud Alcohol. 1994, 55: 207-213.
Article
CAS
PubMed
Google Scholar
Monteiro MG, Klein JL, Schuckit MA: High levels of sensitivity to alcohol in young adult Jewish men: a pilot study. J Stud Alcohol. 1991, 52: 464-469.
Article
CAS
PubMed
Google Scholar
Lander ES, Schork NJ: Genetic dissection of complex traits. Science. 1994, 265: 2037-2048. 10.1126/science.8091226.
Article
CAS
PubMed
Google Scholar
Leland J: Firewater myths: North American Indian drinking and alcohol addiction. 1976, New Brunswick, NJ: Publications Division, Rutgers Center of Alcohol Studies
Google Scholar
Ehlers CL, Garcia-Andrade C, Wall TL, Sobel DF, Phillips E: Determinants of P3 amplitude and response to alcohol in Native American Mission Indians. Neuropsychopharmacology. 1998, 18: 282-292. 10.1016/S0893-133X(97)00160-7.
Article
CAS
PubMed
Google Scholar
Ehlers CL, Garcia-Andrade C, Wall TL, Cloutier D, Phillips E: Electroencephalographic responses to alcohol challenge in Native American Mission Indians. Biol Psychiatry. 1999, 45: 776-787. 10.1016/S0006-3223(98)00113-9.
Article
CAS
PubMed
Google Scholar
Garcia-Andrade C, Wall TL, Ehlers CL: The firewater myth and response to alcohol in Mission Indians. Am J Psychiatry. 1997, 154: 983-988.
Article
CAS
PubMed
Google Scholar
Ehlers CL, Wall TL, Garcia-Andrade C, Phillips E: Auditory P3 findings in Mission Indian youth. J Stud Alcohol. 2001, 62: 562-570.
Article
CAS
PubMed
Google Scholar
Ehlers CL, Wall TL, Garcia-Andrade C, Phillips E: Visual P3 findings in Mission Indian youth: relationship to family history of alcohol dependence and behavioral problems. Psychiatry Res. 2001, 105: 67-78. 10.1016/S0165-1781(01)00313-4.
Article
CAS
PubMed
Google Scholar
Ehlers CL, Wall TL, Garcia-Andrade C, Phillips E: Effects of age and parental history of alcoholism on EEG findings in Mission Indian children and adolescents. Alcohol Clin Exp Res. 2001, 25: 672-679. 10.1111/j.1530-0277.2001.tb02266.x.
Article
CAS
PubMed
Google Scholar
Ehlers CL, Wall TL, Garcia-Andrade C, Phillips E: EEG asymmetry: relationship to mood and risk for alcoholism in Mission Indian youth. Biol Psychiatry. 2001, 50: 129-136. 10.1016/S0006-3223(01)01132-5.
Article
CAS
PubMed
Google Scholar
Ehlers CL, Wall TL, Betancourt M, Gilder DA: The clinical course of alcoholism in 243 Mission Indians. Am J Psychiatry. 2004, 161: 1204-1210. 10.1176/appi.ajp.161.7.1204.
Article
PubMed
Google Scholar
Ehlers CL, Gilder DA, Wall TL, Phillips E, Feiler H, Wilhelmsen KC: Genomic screen for loci associated with alcohol dependence in Mission Indians. Am J Hum Genet. 2004, 129: 110-115.
Article
Google Scholar
Ehlers CL, Slutske WS, Gilder DA, Lau P, Wilhelmsen KC: Age at first intoxication and alcohol use disorders in Southwest California Indians. Alcohol Clin Exp Res. 2006, 30: 1856-1865. 10.1111/j.1530-0277.2006.00222.x.
Article
PubMed
Google Scholar
Wall TL, Garcia-Andrade C, Thomasson HR, Carr LG, Ehlers CL: Alcohol dehydrogenase polymorphisms in Native Americans: identification of the ADH2*3 allele. Alcohol Alcohol. 1997, 32: 129-132.
Article
CAS
PubMed
Google Scholar
Wall TL, Carr LG, Ehlers CL: Protective association of genetic variation in alcohol dehydrogenase with alcohol dependence in Native American Mission Indians. Am J Psychiatry. 2003, 160: 41-46. 10.1176/appi.ajp.160.1.41.
Article
PubMed
Google Scholar
Ehlers CL, Wilhelmsen KC: Genomic scan for alcohol craving in Mission Indians. Psychiatr Genet. 2005, 15: 71-75. 10.1097/00041444-200503000-00012.
Article
PubMed
Google Scholar
Ehlers CL, Wilhelmsen KC: Genomic screen for loci associated with tobacco usage in Mission Indians. BMC Med Genet. 7: 9-10.1186/1471-2350-7-9. 2006, Feb 10;
Ehlers CL, Wilhelmsen KC: Genomic screen for substance dependence and body mass index in Southwest California Indians. Genes Brain Behav. 2007, 6: 184-191. 10.1111/j.1601-183X.2006.00246.x.
Article
PubMed
Google Scholar
Wilhelmsen KC, Ehlers C: Heritability of substance dependence in a Native American population. Psychiatr Genet. 2005, 15: 101-107. 10.1097/00041444-200506000-00006.
Article
PubMed
Google Scholar
Kalton G, Anderson DW: Sampling rare populations. J Roy Stat Soc. 1986, 149: 65-82.
Article
Google Scholar
Muhib FB, Lin LS, Stueve A, Miller RL, Ford WL, Johnson WD, Smith PJ: A venue-based method for sampling hard-to-reach populations. Public Health Rep. 2001, 116 (Suppl 1): 216-222. 10.1093/phr/116.S1.216.
Article
PubMed
PubMed Central
Google Scholar
Heckathorn DD: Respondent-driven sampling: a new approach to the study of hidden populations. Soc Probl. 1997, 44: 174-199. 10.1525/sp.1997.44.2.03x0221m.
Article
Google Scholar
Ehlers CL, Spence JP, Wall TL, Gilder DA, Carr LG: Association of ALDH1 promoter polymorphisms with alcohol-related phenotypes in Southwest California Indians. Alcohol Clin Exp Res. 2004, 28: 1481-1486. 10.1097/01.ALC.0000141821.06062.20.
Article
CAS
PubMed
Google Scholar
Schuckit MA: Genetics and the risk for alcoholism. JAMA. 1985, 254: 2614-2617. 10.1001/jama.254.18.2614.
Article
CAS
PubMed
Google Scholar
Bucholz KK, Cadoret R, Cloninger CR, Dinwiddie SH, Hesselbrock VM, Nurnberger JI, Reich T, Schmidt I, Schuckit MA: A new, semi-structured psychiatric interview for use in genetic linkage studies: a report on the reliability of the SSAGA. J Stud Alcohol. 1994, 55: 149-158.
Article
CAS
PubMed
Google Scholar
American Psychiatric Association, Task Force on DSM-IV: Diagnostic and statistical manual of mental disorders (DSM-IV). 1994, Washington, DC: American Psychiatric Association
Google Scholar
Schuckit MA, Smith TL, Kalmijn J, Tsuang J, Hesselbrock V, Bucholz K: Response to alcohol in daughters of alcoholics: a pilot study and a comparison with sons of alcoholics. Alcohol Alcohol. 2000, 35: 242-248.
Article
CAS
PubMed
Google Scholar
Barrett JC, Fry B, Maller J, Daly MJ: Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics. 2005, 21: 263-265. 10.1093/bioinformatics/bth457.
Article
CAS
PubMed
Google Scholar
International HapMap Public Database. [http://www.hapmap.org]
Applied Biosystems SNP Database. [http://www.appliedbiosystems.com]
PHYLIP. PHYLogeny Inference Package. Department of Genome Sciences, University of Washington, Seattle, WA, [http://evolution.gs.washington.edu/phylip/phylip.html]
SOLAR. Sequential Oligogenic Linkage Analysis Routines. Southwest Foundation for Biomedical Research, San Antonio, TX, [http://www.sfbr.org/solar/]
Almasy L, Blangero J: Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet. 1998, 62: 1198-1211. 10.1086/301844.
Article
CAS
PubMed
PubMed Central
Google Scholar
Ehlers CL, Wall TL, Corey L, Lau P, Gilder DA, Wilhelmsen K: Heritability of illicit drug use and transition to dependence in Southwest California Indians. Psych Genet. 2007, 17: 171-176. 10.1097/01.ypg.0000242201.56342.1a.
Article
Google Scholar
Wigginton JE, Abecasis GR: PEDSTATS: descriptive statistics, graphics and quality assessment for gene mapping data. Bioinformatics. 2005, 21: 3445-3447. 10.1093/bioinformatics/bti529.
Article
CAS
PubMed
Google Scholar
Schuckit MA: Drug and alcohol abuse: a clinical guide to diagnosis and treatment. 1995, New York: Plenum Medical Book Co, 4
Book
Google Scholar
Ehlers CL, Phillips E, Sweeny A, Slawecki CJ: Event-related potential responses to alcohol-related stimuli in African-American young adults: relation to family history of alcoholism and drug usage. Alcohol Alcohol. 2003, 38: 332-338.
Article
PubMed
Google Scholar
Heath AC, Madden PA, Bucholz KK, Dinwiddie SH, Slutske WS, Bierut LJ, Rohrbaugh JW, Statham DJ, Dunne MP, Whitfield JB, Martin NG: Genetic differences in alcohol sensitivity and the inheritance of alcoholism risk. Psychol Med. 1999, 29: 1069-1081. 10.1017/S0033291799008909.
Article
CAS
PubMed
Google Scholar
Schuckit MA, Wilhelmsen K, Smith TL, Feiler HS, Lind P, Lange LA, Kalmijn J: Autosomal linkage analysis for the level of response to alcohol. Alcohol Clin Exp Res. 2005, 29: 1976-1982. 10.1097/01.alc.0000187598.82921.27.
Article
PubMed
Google Scholar
Kim SG, Kim CM, Kang DH, Kim YJ, Byun WT, Kim SY, Park JM, Kim MJ, Oslin DW: Association of functional opioid receptor genotypes with alcohol dependence in Koreans. Alcohol Clin Exp Res. 2004, 28: 986-990. 10.1097/01.ALC.0000130803.62768.AB.
Article
CAS
PubMed
Google Scholar
Ray LA, Hutchison KE: Effects of naltrexone on alcohol sensitivity and genetic moderators of medication response: a double-blind placebo-controlled study. Arch Gen Psychiatry. 2007, 64: 1069-1077. 10.1001/archpsyc.64.9.1069.
Article
CAS
PubMed
Google Scholar
Ray LA, Hutchison KE: A polymorphism of the mu-opioid receptor gene (OPRM1) and sensitivity to the effects of alcohol in humans. Alcohol Clin Exp Res. 2004, 28: 1789-1795. 10.1097/01.ALC.0000148114.34000.B9.
Article
CAS
PubMed
Google Scholar
Ide S, Kobayashi H, Ujike H, Ozaki N, Sekine Y, Inada T, Harano M, Komiyama T, Yamada M, Iyo M, Iwata N, Tanaka K, Shen H, Iwahashi K, Itokawa M, Minami M, Satoh M, Ikeda K, Sora I: Linkage disequilibrium and association with methamphetamine dependence/psychosis of mu-opioid receptor gene polymorphisms. Pharmacogenomics J. 2006, 6: 179-188. 10.1038/sj.tpj.6500355.
Article
CAS
PubMed
Google Scholar
Luo X, Kranzler HR, Zhao H, Gelernter J: Haplotypes at the OPRM1 locus are associated with susceptibility to substance dependence in European-Americans. Am J Med Genet B Neuropsychiatr Genet. 2003, 120: 97-108. 10.1002/ajmg.b.20034.
Article
Google Scholar
Zhang D, Shao C, Shao M, Yan P, Wang Y, Liu Y, Liu W, Lin T, Xie Y, Zhao Y, Lu D, Li Y, Jin L: Effect of mu-opioid receptor gene polymorphisms on heroin-induced subjective responses in a Chinese population. Biol Psychiatry. 2007, 61: 1244-1251. 10.1016/j.biopsych.2006.07.012.
Article
CAS
PubMed
Google Scholar
Zhang H, Luo X, Kranzler HR, Lappalainen J, Yang BZ, Krupitsky E, Zvartau E, Gelernter J: Association between two mu-opioid receptor gene (OPRM1) haplotype blocks and drug or alcohol dependence. Hum Mol Genet. 2006, 15: 807-819. 10.1093/hmg/ddl024.
Article
CAS
PubMed
PubMed Central
Google Scholar
Xuei X, Flury-Wetherill L, Bierut L, Dick D, Nurnberger J, Foroud T, Edenberg HJ: The opioid system in alcohol and drug dependence: family-based association study. Am J Med Genet B Neuropsychiatr Genet. 2007, 144: 877-884.
Article
Google Scholar
Zhang L, Kendler KS, Chen X: The mu-opioid receptor gene and smoking initiation and nicotine dependence. Behav Brain Funct. 2006, 2: 28-10.1186/1744-9081-2-28.
Article
PubMed
PubMed Central
Google Scholar
Smith RJ, Doyle GA, Han AM, Crowley JJ, Oslin DW, Patkar AA, Mannelli P, Demaria PA, O'Brien CP, Berrettini WH: Novel exonic mu-opioid receptor gene (OPRM1) polymorphisms not associated with opioid dependence. Am J Med Genet B Neuropsychiatr Genet. 2005, 133: 105-109.
Article
Google Scholar
Crowley JJ, Oslin DW, Patkar AA, Gottheil E, Demaria PA, O'Brien CP, Berrettini WH, Grice DE: A genetic association study of the mu opioid receptor and severe opioid dependence. Psychiatr Genet. 2003, 13: 169-173. 10.1097/00041444-200309000-00006.
Article
PubMed
Google Scholar
Shi J, Hui L, Xu Y, Wang F, Huang W, Hu G: Sequence variations in the mu-opioid receptor gene (OPRM1) associated with human addiction to heroin. Hum Mutat. 2002, 19: 459-460. 10.1002/humu.9026.
Article
PubMed
Google Scholar