Assadi F. The growing epidemic of hypertension among children and adolescents: a challenging road ahead. Pediatr Cardiol. 2012;33(7):1013–20. doi:10.1007/s00246-012-0333-5.
Article
PubMed
Google Scholar
Kaplan İ, Sancaktar E, Ece A, Şen V, Tekkeşin N, Basarali MK, et al. Gene polymorphisms of adducin GLY460TRP, ACE I/D, AND AGT M235T in pediatric hypertension patients. Med Sci Monit. 2014;20:1745–50. doi:10.12659/MSM.892140.
Article
CAS
PubMed
PubMed Central
Google Scholar
Dulskiene V, Kuciene R, Medzioniene J, Benetis R. Association between obesity and high blood pressure among Lithuanian adolescents: a cross-sectional study. Ital J Pediatr. 2014;40:102. doi:10.1186/s13052-014-0102-6.
Article
PubMed
PubMed Central
Google Scholar
Tamosiunas A, Luksiene D, Baceviciene M, Bernotiene G, Radisauskas R, Malinauskiene V, et al. Health factors and risk of all-cause, cardiovascular, and coronary heart disease mortality: findings from the MONICA and HAPIEE studies in Lithuania. PLoS One. 2014;9(12):e114283. doi:10.1371/journal.pone.0114283.
Article
PubMed
PubMed Central
Google Scholar
Reklaitiene R, Tamosiunas A, Virviciute D, Baceviciene M, Luksiene D. Trends in prevalence, awareness, treatment, and control of hypertension, and the risk of mortality among middle-aged Lithuanian urban population in 1983-2009. BMC Cardiovasc Disord. 2012 Aug 31;12:68. doi:10.1186/1471-2261-12-68.
Article
PubMed
PubMed Central
Google Scholar
Zaborskis A, Petrauskiene A, Gradeckiene S, Vaitkaitiene E, Bartasiūte V. Overweight and increased blood pressure in preschool-aged children. Medicina (Kaunas). 2003;39(12):1200–7.
Google Scholar
Grabauskas V, Klumbiene J, Petkeviciene J, Petrauskiene A, Tamosiūnas A, Kriaucioniene V, et al. Risk factors for noncommunicable diseases in Lithuanian rural population: CINDI survey 2007. Medicina (Kaunas). 2008;44(8):633–9.
Google Scholar
Chen X, Wang Y. Tracking of blood pressure from childhood to adulthood: a systematic review and meta-regression analysis. Circulation. 2008;117(25):3171–80. https://doi.org/10.1161/CIRCULATIONAHA.107.730366.
Article
PubMed
PubMed Central
Google Scholar
Petkeviciene J, Klumbiene J, Simonyte S, Ceponiene I, Jureniene K, Kriaucioniene V, et al. V. Physical, behavioural and genetic predictors of adult hypertension: the findings of the Kaunas Cardiovascular Risk Cohort study. PLoS One. 2014;9(10):e109974. doi:10.1371/journal.pone.0109974.
Article
PubMed
PubMed Central
Google Scholar
Klumbiene J, Sileikiene L, Milasauskiene Z, Zaborskis A, Shatckute A. The relationship of childhood to adult blood pressure: longitudinal study of juvenile hypertension in Lithuania. J Hypertens. 2000;18:531–9.
Article
CAS
PubMed
Google Scholar
Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, et al. The seventh report of the joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure: the JNC 7 report. JAMA. 2003;289(19):2560–72.
Article
CAS
PubMed
Google Scholar
Brady TM, Fivush B, Flynn JT, Parekh R. Ability of blood pressure to predict left ventricular hypertrophy in children with primary hypertension. J Pediatr. 2008;152(1):73–8. 78.e1
Article
PubMed
Google Scholar
Sorof JM, Alexandrov AV, Garami Z, Turner JL, Grafe RE, Lai D, et al. Carotid ultrasonography for detection of vascular abnormalities in hypertensive children. Pediatr Nephrol. 2003;18(10):1020–4.
Article
PubMed
Google Scholar
Williams SS. Advances in genetic hypertension. Curr Opin Pediatr. 2007;19(2):192–8.
Article
PubMed
Google Scholar
Fava C, Philippe B, Almgren P, Groop L, Hulthén UL, Melander O. Heritability of ambulatory and office blood pressure phenotypes in Swedish families. J of Hyperten. 2004;9:1717–21.
Article
Google Scholar
Kupper N, Willemsen G, Riese H, Posthuma D, Boomsma DI, de Geus EJ. Heritability of daytime ambulatory blood pressure in an extended twin design. Hypertension. 2005;45:80–5.
Article
CAS
PubMed
Google Scholar
Poch E1, González D, Giner V, Bragulat E, Coca A, de La Sierra A. Molecular Basis of Salt Sensitivity in Human Hypertension. Hyperten. 2001;38:1204–9.
Article
CAS
Google Scholar
Beevers G, Lip GY, O'Brien E. ABC of hypertension: the pathophysiology of hypertension. BMJ. 2001;322(7291):912–6.
Article
CAS
PubMed
PubMed Central
Google Scholar
Yazdanpanah M, Aulchenko YS, Hofman A, Janssen JA, Sayed-Tabatabaei FA, van Schaik RH, et al. Effects of the renin-angiotensin system genes and salt sensitivity genes on blood pressure and atherosclerosis in the total population and patients with type 2 diabetes. Diabetes. 2007;56(7):1905–12.
Article
CAS
PubMed
Google Scholar
Luft FC. Twins in cardiovascular genetic research. Hypertension. 2001;37(2 Pt 2):350–6.
Article
CAS
PubMed
Google Scholar
Singh M, Mensah GA, Bakris G. Pathogenesis and clinical physiology of hypertension. Cardiol Clin. 2010;28(4):545–59. doi:10.1016/j.ccl.2010.07.001.
Article
PubMed
Google Scholar
Xue H, Lu Z, Tang WL, Pang LW, Wang GM, Wong GW, et al. First-line drugs inhibiting the renin angiotensin system versus other first-line antihypertensive drug classes for hypertension. Cochrane Database Syst Rev. 2015;1:CD008170. doi:10.1002/14651858.CD008170.pub2.
PubMed
Google Scholar
Jeunemaitre X, Soubrier F, Kotelevtsev YV, Lifton RP, Williams CS, Charru A, et al. Molecular basis of human hypertension: role of angiotensinogen. Cell. 1992;71(1):169–80.
Article
CAS
PubMed
Google Scholar
Lele RD. Hypertension: molecular approach. J Assoc Physicians India. 2004;52:53–62.
CAS
PubMed
Google Scholar
Mondry A, Loh M, Liu P, Zhu AL, Nagel M. Polymorphisms of the insertion / deletion ACE and M235T AGT genes and hypertension: surprising new findings and meta-analysis of data. BMC Nephrol. 2005;6:1.
Article
PubMed
PubMed Central
Google Scholar
Nantel P, René de Cotret P. The evolution of angiotensin blockade in the management of cardiovascular disease. Can J Cardiol. 2010;26(Suppl E):7E–13E. doi:10.1016/S0828-282X(10)71168-5.
Article
PubMed
Google Scholar
Chaves FJ, Pascual JM, Rovira E, Armengod ME, Redon J. Angiotensin II AT1 receptor gene polymorphism and microalbuminuria in essential hypertension. Am J Hypertens. 2001;14(4 Pt 1):364–70.
Article
CAS
PubMed
Google Scholar
Bonnardeaux A, Davies E, Jeunemaitre X, Féry I, Charru A, Clauser E, Tiret L, Cambien F, Corvol P, Soubrier F. Angiotensin II type 1 receptor gene polymorphisms in human essential hypertension. Hypertension. 1994;24(1):63–9.
Article
CAS
PubMed
Google Scholar
Wang WY, Zee RY, Morris BJ. Association of angiotensin II type 1 receptor gene polymorphism with essential hypertension. Clin Genet. 1997;51(1):31–4.
Article
CAS
PubMed
Google Scholar
National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents. The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics. 2004;114(2 Suppl 4th Report):555–576.
Cole TJ, Bellizzi MC, Flegal KM, Dietz WH. Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ. 2000;320(7244):1240–3.
Article
CAS
PubMed
PubMed Central
Google Scholar
Fernández JR, Redden DT, Pietrobelli A, Allison DB. Waist circumference percentiles in nationally representative samples of African-American, European-American, and Mexican-American children and adolescents. J Pediatr. 2004;145(4):439–44.
Article
PubMed
Google Scholar
Mayer NJ, Forsynth A, Kantachuvesiri S, Mullins JJ, Fleming S. Association of the D allele of the angiotensin I converting enzyme polymorphism with malignant vascular injury. J Clin Pathol Mol Pathol. 2002;55:29–33.
Article
CAS
Google Scholar
Ramos E, Barros H. Prevalence of hypertension in 13-year-old adolescents in Porto. Portugal Rev Port Cardiol. 2005;24(9):1075–87.
PubMed
Google Scholar
McNiece KL, Poffenbarger TS, Turner JL, Franco KD, Sorof JM, Portman RJ. Prevalence of hypertension and pre-hypertension among adolescents. J Pediatr. 2007;150(6):640–4.
Article
PubMed
Google Scholar
Mehdad S, Hamrani A, El Kari K, El Hamdouchi A, El Mzibri M, Barkat A, et al. Prevalence of elevated blood pressure and its relationship with fat mass, body mass index and waist circumference among a group of Moroccan overweight adolescents. Obes Res Clin Pract. 2013;7(4):e284–9. https://doi.org/10.1016/j.orcp.2012.02.006.
Article
PubMed
Google Scholar
Brug J, van Stralen MM, Te Velde SJ, Chinapaw MJ, De Bourdeaudhuij I, Lien N, et al. Differences in weight status and energy-balance related behaviors among schoolchildren across Europe: the ENERGY-project. PLoS One. 2012;7(4):e34742. doi:10.1371/journal.pone.0034742.
Article
CAS
PubMed
PubMed Central
Google Scholar
Smetanina N, Albaviciute E, Babinska V, Karinauskiene L, Albertsson-Wikland K, Petrauskiene A, et al. Prevalence of overweight/obesity in relation to dietary habits and lifestyle among 7-17 years old children and adolescents in Lithuania. BMC Public Health. 2015;15:1001. doi:10.1186/s12889-015-2340-y.
Article
PubMed
PubMed Central
Google Scholar
Kunešová M, Vignerová J, Pařízková J, Procházka B, Braunerová R, Riedlová J, et al. Long-term changes in prevalence of overweight and obesity in Czech 7-year-old children: evaluation of different cut-off criteria of childhood obesity. Obes Rev. 2011;12(7):483–91. doi:10.1111/j.1467-789X.2011.00870.x.
Article
PubMed
Google Scholar
Valdés Pizarro J, Royo-Bordonada MA. Prevalence of childhood obesity in Spain: National Health Survey 2006-2007. Nutr Hosp. 2012;27(1):154–60. doi:10.1590/S0212-16112012000100018.
PubMed
Google Scholar
Bac A, Woźniacka R, Matusik S, Golec J, Golec E. Prevalence of overweight and obesity in children aged 6-13 years-alarming increase in obesity in Cracow. Poland Eur J Pediatr. 2012;171(2):245–51. doi:10.1007/s00431-011-1519-1.
Article
PubMed
Google Scholar
Wirix AJ, Verheul J, Groothoff JW, Nauta J, Chinapaw MJ, Kist-van Holthe JE. Screening, diagnosis and treatment of hypertension in obese children: an international policy comparison. J Nephrol. 2017;30(1):119–25. doi:10.1007/s40620-016-0277-6.
Article
PubMed
Google Scholar
Lu X, Shi P, Luo CY, Zhou YF, Yu HT, Guo CY, et al. Prevalence of hypertension in overweight and obese children from a large school-based population in shanghai. China BMC Public Health. 2013;13:24. doi:10.1186/1471-2458-13-24.
Article
PubMed
Google Scholar
Sorof JM, Lai D, Turner J, Poffenbarger T, Portman RJ. Overweight, ethnicity, and the prevalence of hypertension in school-aged children. Pediatrics. 2004;113(3 Pt 1):475–82.
Article
PubMed
Google Scholar
Field AE, Cook NR, Gillman MW. Weight status in childhood as a predictor of becoming overweight or hypertensive in early adulthood. Obes Res. 2005;13(1):163–9.
Article
PubMed
PubMed Central
Google Scholar
Juhola J, Oikonen M, Magnussen CG, Mikkilä V, Siitonen N, Jokinen E, et al. Childhood physical, environmental, and genetic predictors of adult hypertension: the cardiovascular risk in young Finns study. Circulation. 2012;126(4):402–9. doi:10.1161/CIRCULATIONAHA.111.085977.
Article
PubMed
Google Scholar
Sethi AA, Nordestgaard BG, Agerholm-Larsen B, Frandsen E, Jensen G. Tybjaerg-Hansen. Angiotensinogen polymorphisms and elevated blood pressure in the general population: the Copenhagen City heart study. Hypertension. 2001 Mar;37(3):875–81.
Article
CAS
PubMed
Google Scholar
Inoue I, Nakajima T, Williams CS, Quackenbush J, Puryear R, Powers M, et al. A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and effects basal transcription in vitro. J Clin Invest. 1997;99(7):1786–97.
Article
CAS
PubMed
PubMed Central
Google Scholar
Mattace-Raso FUS, Sie MPS, van der Cammen TJM, Safar ME, Hofman A, van Duijn CM, Witteman JCM. Insertion/deletion gene polymorphism of the angiotensin-converting enzyme and blood pressure changes in older adults. The Rotterdam study. J Human Hyperten. 2007;21:736–40.
Article
CAS
Google Scholar
Papp F, Friedman AL, Bereczki C, Haszon I, Kiss E, Endreffy E, et al. Renin-angiotensin gene polymorphism in children with uremia and essential hypertension. Pediatr Nephrol. 2003;18(2):150–4.
PubMed
Google Scholar
Lemes VA, Neves AL, Guazzelli IC, Frazzatto E, Nicolau C, Corrêa-Giannella ML, et al. Angiotensin converting enzyme insertion/deletion polymorphism is associated with increased adiposity and blood pressure in obese children and adolescents. Gene. 2013;532(2):197–202. doi:10.1016/j.gene.2013.09.065.
Article
CAS
PubMed
Google Scholar
Dhanachandra Singh K, Jajodia A, Kaur H, Kukreti R, Karthikeyan M. Gender specific association of RAS gene polymorphism with essential hypertension: a case-control study. Biomed Res Int. 2014;2014:538053. doi:10.1155/2014/538053.
Article
PubMed
PubMed Central
Google Scholar
Fornage M, Amos CI, Kardia S, Sing CF, Turner ST, Boerwinkle E. Variation in the region of the angiotensin-converting enzyme gene influences interindividual differences in blood pressure levels in young white males. Circulation. 1998;97(18):1773–9.
Article
CAS
PubMed
Google Scholar
O'Donnell CJ, Lindpaintner K, Larson MG, Rao VS, Ordovas JM, Schaefer EJ, et al. Evidence for association and genetic linkage of the angiotensin-converting enzyme locus with hypertension and blood pressure in men but not women in the Framingham heart study. Circulation. 1998;97(18):1766–72.
Article
PubMed
Google Scholar
Di Pasquale P, Cannizzaro S, Paterna S. Does angiotensin-converting enzyme gene polymorphism affect blood pressure? Findings after 6 years of follow-up in healthy subjects. Eur J Heart Fail. 2004;6(1):11–6.
Article
PubMed
Google Scholar
Hilliard LM, Sampson AK, Brown RD, Denton KM. The “his and hers” of the renin-angiotensin system. Curr Hypertens Rep. 2013;15(1):71–9. doi:10.1007/s11906-012-0319.
Article
CAS
PubMed
Google Scholar
Grady D, Rubin SM, Petitti DB, Fox CS, Black D, Ettinger B, et al. Hormone therapy to prevent disease and prolong life in postmenopausal women. Ann Intern Med. 1992;117(12):1016–37.
Article
CAS
PubMed
Google Scholar
Bonnardeaux A, Davies E, Jeunemaitre X, Féry I, Charru A, Clauser E, et al. Angiotensin II type 1 receptor gene polymorphisms in human essential hypertension. Hypertension. 1994;24(1):63–9.
Article
CAS
PubMed
Google Scholar
Wang JL, Xue L, Hao PP, Xu F, Chen YG, Zhang Y. Angiotensin II type 1 receptor gene A1166C polymorphism and essential hypertension in Chinese: a meta-analysis. J Renin-Angiotensin-Aldosterone Syst. 2010;11(2):127–35. doi:10.1177/1470320310364181.
Article
CAS
PubMed
Google Scholar
Mehri S, Mahjoub S, Hammami S, Zaroui A, Frih A, Betbout F, et al. Renin-angiotensin system polymorphisms in relation to hypertension status and obesity in a Tunisian population. Mol Biol Rep. 2012;39(4):4059–65. doi:10.1007/s11033-011-1187-2.
Article
CAS
PubMed
Google Scholar
Sugimoto K, Katsuya T, Ohkubo T, Hozawa A, Yamamoto K, Matsuo A, et al. Association between angiotensin II type 1 receptor gene polymorphism and essential hypertension: the Ohasama study. Hypertens Res. 2004;27(8):551–6.
Article
CAS
PubMed
Google Scholar
Minority Rights Group International, World directory of minorities and indigenous peoples - Lithuania, 2007, available at: http://www.refworld.org/docid/4954ce4f23.html. [Accessed 10 Aug 2017].
Lithuania S. Lithuanian 2011 population census in brief. Vilnius, Lithuania: Statistics Lithuania; 2012. https://osp.stat.gov.lt/documents/10180/217110/Gyv_kalba_tikyba.pdf/1d9dac9a-3d45-4798-93f5-941fed00503f.
Google Scholar
Grimes DA, Schulz KF. Bias and causal associations in observational research. Lancet. 2002;359(9302):248–52.
Article
PubMed
Google Scholar