Greco L, Corazza G, Babron MC, Clot F, Fulchignoni-Lataud MC, Percopo S, Zavattari P, Bouguerra F, Dib C, Tosi R, et al: Genome search in celiac disease. Am J Hum Genet. 1998, 62 (3): 669-675. 10.1086/301754.
Article
CAS
PubMed
PubMed Central
Google Scholar
Holopainen P, Mustalahti K, Uimari P, Collin P, Maki M, Partanen J: Candidate gene regions and genetic heterogeneity in gluten sensitivity. Gut. 2001, 48 (5): 696-701. 10.1136/gut.48.5.696.
Article
CAS
PubMed
PubMed Central
Google Scholar
Naluai AT, Nilsson S, Gudjonsdottir AH, Louka AS, Ascher H, Ek J, Hallberg B, Samuelsson L, Kristiansson B, Martinsson T, et al: Genome-wide linkage analysis of Scandinavian affected sib-pairs supports presence of susceptibility loci for celiac disease on chromosomes 5 and 11. Eur J Hum Genet. 2001, 9 (12): 938-944. 10.1038/sj.ejhg.5200752.
Article
CAS
PubMed
Google Scholar
van Heel DA, Franke L, Hunt KA, Gwilliam R, Zhernakova A, Inouye M, Wapenaar MC, Barnardo MC, Bethel G, Holmes GK, et al: A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21. Nat Genet. 2007, 39 (7): 827-829. 10.1038/ng2058.
Article
CAS
PubMed
PubMed Central
Google Scholar
Dubois PC, Trynka G, Franke L, Hunt KA, Romanos J, Curtotti A, Zhernakova A, Heap GA, Adany R, Aromaa A, et al: Multiple common variants for celiac disease influencing immune gene expression. Nat Genet. 2010, 42 (4): 295-302. 10.1038/ng.543.
Article
CAS
PubMed
PubMed Central
Google Scholar
Louka AS, Stensby EK, Ek J, Gudjonsdottir AH, Ascher H, Sollid LM: Coeliac disease candidate genes: no association with functional polymorphisms in matrix metalloproteinase 1 and 3 gene promoters. Scand J Gastroenterol. 2002, 37 (8): 931-935. 10.1080/003655202760230892.
Article
CAS
PubMed
Google Scholar
Mora B, Bonamico M, Ferri M, Megiorni F, Osborn J, Pizzuti A, Mazzilli MC: Association of the matrix metalloproteinase-3 (MMP-3) promoter polymorphism with celiac disease in male subjects. Hum Immunol. 2005, 66 (6): 716-720. 10.1016/j.humimm.2005.02.005.
Article
CAS
PubMed
Google Scholar
Dadi HK, Simon AJ, Roifman CM: Effect of CD3delta deficiency on maturation of alpha/beta and gamma/delta T-cell lineages in severe combined immunodeficiency. N Engl J Med. 2003, 349 (19): 1821-1828. 10.1056/NEJMoa031178.
Article
CAS
PubMed
Google Scholar
de Saint Basile G, Geissmann F, Flori E, Uring-Lambert B, Soudais C, Cavazzana-Calvo M, Durandy A, Jabado N, Fischer A, Le Deist F: Severe combined immunodeficiency caused by deficiency in either the delta or the epsilon subunit of CD3. J Clin Invest. 2004, 114 (10): 1512-1517.
Article
Google Scholar
Ghabanbasani MZ, Buyse I, Legius E, Decorte R, Marynen P, Bouillon R, Cassiman JJ: Possible association of CD3 and CD4 polymorphisms with insulin-dependent diabetes mellitus (IDDM). Clin Exp Immunol. 1994, 97 (3): 517-521. 10.1111/j.1365-2249.1994.tb06119.x.
Article
CAS
PubMed
PubMed Central
Google Scholar
Rege TA, Hagood JS: Thy-1, a versatile modulator of signaling affecting cellular adhesion, proliferation, survival, and cytokine/growth factor responses. Biochim Biophys Acta. 2006, 1763 (10): 991-999. 10.1016/j.bbamcr.2006.08.008.
Article
CAS
PubMed
PubMed Central
Google Scholar
Moore KW, de Waal Malefyt R, Coffman RL, O'Garra A: Interleukin-10 and the interleukin-10 receptor. Annu Rev Immunol. 2001, 19: 683-765. 10.1146/annurev.immunol.19.1.683.
Article
CAS
PubMed
Google Scholar
Gasche C, Grundtner P, Zwirn P, Reinisch W, Shaw SH, Zdanov A, Sarma U, Williams LM, Foxwell BM, Gangl A: Novel variants of the IL-10 receptor 1 affect inhibition of monocyte TNF-alpha production. J Immunol. 2003, 170 (11): 5578-5582.
Article
CAS
PubMed
Google Scholar
Daly JS, McManus R, Farrell R, Weir DG, Kelleher D: Tumour necrosis factor-a production significantly increased in coeliac disease is not associated with the TNFa2 microsatellite polymorphism. Immunology Letters. 1997, 56 (1): 40-41. 10.1016/S0165-2478(97)86992-1.
Article
Google Scholar
Turner DM, Williams DM, Sankaran D, Lazarus M, Sinnott PJ, Hutchinson IV: An investigation of polymorphism in the interleukin-10 gene promoter. Eur J Immunogenet. 1997, 24 (1): 1-8.
Article
CAS
PubMed
Google Scholar
Hahn-Zoric M, Hytonen AM, Hanson LA, Nilsson LA, Padyukov L: Association of -1087 IL10 and -308 TNFA gene polymorphisms with serological markers of coeliac disease. J Clin Immunol. 2003, 23 (4): 291-296. 10.1023/A:1024588800754.
Article
CAS
PubMed
Google Scholar
Lio D, Scola L, Forte GI, Accomando S, Giacalone A, Crivello A, Cataldo F: TNFalpha, IFNgamma and IL-10 gene polymorphisms in a sample of Sicilian patients with coeliac disease. Dig Liver Dis. 2005, 37 (10): 756-760. 10.1016/j.dld.2005.04.027.
Article
CAS
PubMed
Google Scholar
Salvati VM, Mazzarella G, Gianfrani C, Levings MK, Stefanile R, De Giulio B, Iaquinto G, Giardullo N, Auricchio S, Roncarolo MG, et al: Recombinant human interleukin 10 suppresses gliadin dependent T cell activation in ex vivo cultured coeliac intestinal mucosa. Gut. 2005, 54 (1): 46-53. 10.1136/gut.2003.023150.
Article
CAS
PubMed
PubMed Central
Google Scholar
McInnes IB, Gracie JA, Leung BP, Wei XQ, Liew FY: Interleukin 18: a pleiotropic participant in chronic inflammation. Immunol Today. 2000, 21 (7): 312-315. 10.1016/S0167-5699(00)01648-0.
Article
CAS
PubMed
Google Scholar
Gracie JA, Forsey RJ, Chan WL, Gilmour A, Leung BP, Greer MR, Kennedy K, Carter R, Wei XQ, Xu D, et al: A proinflammatory role for IL-18 in rheumatoid arthritis. J Clin Invest. 1999, 104 (10): 1393-1401. 10.1172/JCI7317.
Article
CAS
PubMed
PubMed Central
Google Scholar
Tanaka H, Miyazaki N, Oashi K, Teramoto S, Shiratori M, Hashimoto M, Ohmichi M, Abe S: IL-18 might reflect disease activity in mild and moderate asthma exacerbation. J Allergy Clin Immunol. 2001, 107 (2): 331-336. 10.1067/mai.2001.112275.
Article
CAS
PubMed
Google Scholar
Giedraitis V, He B, Huang WX, Hillert J: Cloning and mutation analysis of the human IL-18 promoter: a possible role of polymorphisms in expression regulation. J Neuroimmunol. 2001, 112 (1-2): 146-152. 10.1016/S0165-5728(00)00407-0.
Article
CAS
PubMed
Google Scholar
Barbaux S, Poirier O, Godefroy T, Kleinert H, Blankenberg S, Cambien F, Tiret L: Differential haplotypic expression of the interleukin-18 gene. Eur J Hum Genet. 2007, 15 (8): 856-863. 10.1038/sj.ejhg.5201842.
Article
CAS
PubMed
Google Scholar
Kretowski A, Mironczuk K, Karpinska A, Bojaryn U, Kinalski M, Puchalski Z, Kinalska I: Interleukin-18 promoter polymorphisms in type 1 diabetes. Diabetes. 2002, 51 (11): 3347-3349. 10.2337/diabetes.51.11.3347.
Article
CAS
PubMed
Google Scholar
Tamura K, Fukuda Y, Sashio H, Takeda N, Bamba H, Kosaka T, Fukui S, Sawada K, Satomi M, Yamada T, et al: IL18 polymorphism is associated with an increased risk of Crohn's disease. J Gastroenterol. 2002, 37 (Suppl 14): 111-116.
Article
CAS
PubMed
Google Scholar
Novak N, Kruse S, Potreck J, Maintz L, Jenneck C, Weidinger S, Fimmers R, Bieber T: Single nucleotide polymorphisms of the IL18 gene are associated with atopic eczema. J Allergy Clin Immunol. 2005, 115 (4): 828-833. 10.1016/j.jaci.2005.01.030.
Article
CAS
PubMed
Google Scholar
Aizawa Y, Sutoh S, Matsuoka M, Negishi M, Torii A, Miyakawa Y, Sugisaka H, Nakamura M, Toda G: Association of interleukin-18 gene single-nucleotide polymorphisms with susceptibility to inflammatory bowel disease. Tissue Antigens. 2005, 65 (1): 88-92. 10.1111/j.1399-0039.2005.00336.x.
Article
CAS
PubMed
Google Scholar
Higa S, Hirano T, Mayumi M, Hiraoka M, Ohshima Y, Nambu M, Yamaguchi E, Hizawa N, Kondo N, Matsui E, et al: Association between interleukin-18 gene polymorphism 105A/C and asthma. Clin Exp Allergy. 2003, 33 (8): 1097-1102. 10.1046/j.1365-2222.2003.01739.x.
Article
CAS
PubMed
Google Scholar
Rueda B, Zhernakova A, Lopez-Nevot MA, Martin J, Koeleman BP: Association study of functional genetic variants of innate immunity related genes in celiac disease. BMC Med Genet. 2005, 6: 29-10.1186/1471-2350-6-29.
Article
CAS
PubMed
PubMed Central
Google Scholar
Rueda B, Gonzalez-Gay MA, Mataran L, Lopez-Nevot MA, Martin J: Interleukin-18-promoter polymorphisms are not relevant in rheumatoid arthritis. Tissue Antigens. 2005, 65 (6): 544-548. 10.1111/j.1399-0039.2005.00408.x.
Article
CAS
PubMed
Google Scholar
Novota P, Kolostova K, Pinterova D, Novak J, Treslova L, Andel M, Cerna M: Interleukin IL-18 gene promoter polymorphisms in adult patients with type 1 diabetes mellitus and latent autoimmune diabetes in adults. Immunol Lett. 2005, 96 (2): 247-251. 10.1016/j.imlet.2004.08.016.
Article
CAS
PubMed
Google Scholar
Ide A, Kawasaki E, Abiru N, Sun F, Fukushima T, Ishii R, Takahashi R, Kuwahara H, Fujita N, Kita A, et al: Association of interleukin-18 gene promoter polymorphisms in type 1 diabetes and autoimmune thyroid disease. Ann N Y Acad Sci. 2003, 1005: 436-439. 10.1196/annals.1288.074.
Article
CAS
PubMed
Google Scholar
Martin RJ, Savage DA, Carson DJ, Maxwell AP, Patterson CC: Interleukin 18 promoter polymorphisms are not strongly associated with type I diabetes in a UK population. Genes Immun. 2005, 6 (2): 171-174. 10.1038/sj.gene.6364161.
Article
CAS
PubMed
Google Scholar
Folwaczny M, Glas J, Torok HP, Tonenchi L, Paschos E, Bauer B, Limbersky O, Folwaczny C: Polymorphisms of the interleukin-18 gene in periodontitis patients. J Clin Periodontol. 2005, 32 (5): 530-534. 10.1111/j.1600-051X.2005.00711.x.
Article
CAS
PubMed
Google Scholar
Hunt KA, Zhernakova A, Turner G, Heap GA, Franke L, Bruinenberg M, Romanos J, Dinesen LC, Ryan AW, Panesar D, et al: Newly identified genetic risk variants for celiac disease related to the immune response. Nat Genet. 2008, 40 (4): 395-402. 10.1038/ng.102.
Article
CAS
PubMed
PubMed Central
Google Scholar
Raymond M, Rousset F: GENEPOP (version 1.2): population genetics software for exact tests and ecumenicism. J Heredity. 1995, 86: 248-249.
Google Scholar
Schaid DJ, Rowland CM, Tines DE, Jacobson RM, Poland GA: Score tests for association between traits and haplotypes when linkage phase is ambiguous. Am J Hum Genet. 2002, 70 (2): 425-434. 10.1086/338688.
Article
PubMed
Google Scholar
Stephens M, Smith NJ, Donnelly P: A new statistical method for haplotype reconstruction from population data. Am J Hum Genet. 2001, 68 (4): 978-989. 10.1086/319501.
Article
CAS
PubMed
PubMed Central
Google Scholar
Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, Bender D, Maller J, Sklar P, de Bakker PI, Daly MJ, et al: PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet. 2007, 81 (3): 559-575. 10.1086/519795.
Article
CAS
PubMed
PubMed Central
Google Scholar
Cardon LR, Palmer LJ: Population stratification and spurious allelic association. Lancet. 2003, 361 (9357): 598-604. 10.1016/S0140-6736(03)12520-2.
Article
PubMed
Google Scholar
Colhoun HM, McKeigue PM, Davey Smith G: Problems of reporting genetic associations with complex outcomes. Lancet. 2003, 361 (9360): 865-872. 10.1016/S0140-6736(03)12715-8.
Article
PubMed
Google Scholar
Tabor HK, Risch NJ, Myers RM: Candidate-gene approaches for studying complex genetic traits: practical considerations. Nat Rev Genet. 2002, 3 (5): 391-397. 10.1038/nrg796.
Article
CAS
PubMed
Google Scholar
Purcell S, Cherny SS, Sham PC: Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics. 2003, 19 (1): 149-150. 10.1093/bioinformatics/19.1.149.
Article
CAS
PubMed
Google Scholar
Gracie JA, Koyama N, Murdoch J, Field M, McGarry F, Crilly A, Schobel A, Madhok R, Pons-Kuhnemann J, McInnes IB, et al: Disease association of two distinct interleukin-18 promoter polymorphisms in Caucasian rheumatoid arthritis patients. Genes Immun. 2005, 6 (3): 211-216. 10.1038/sj.gene.6364183.
Article
CAS
PubMed
Google Scholar
Brophy K, Ryan AW, Thornton JM, Abuzakouk M, Fitzgerald AP, McLoughlin RM, O'Morain C, Kennedy NP, Stevens FM, Feighery C, et al: Haplotypes in the CTLA4 region are associated with coeliac disease in the Irish population. Genes Immun. 2006, 7 (1): 19-26. 10.1038/sj.gene.6364265.
Article
CAS
PubMed
Google Scholar
Djilali-Saiah I, Schmitz J, Harfouch-Hammoud E, Mougenot JF, Bach JF, Caillat-Zucman S: CTLA-4 gene polymorphism is associated with predisposition to coeliac disease. Gut. 1998, 43 (2): 187-189. 10.1136/gut.43.2.187.
Article
CAS
PubMed
PubMed Central
Google Scholar
Smyth DJ, Plagnol V, Walker NM, Cooper JD, Downes K, Yang JH, Howson JM, Stevens H, McManus R, Wijmenga C, et al: Shared and distinct genetic variants in type 1 diabetes and celiac disease. N Engl J Med. 2008, 359 (26): 2767-2777. 10.1056/NEJMoa0807917.
Article
CAS
PubMed
PubMed Central
Google Scholar
Leon AJ, Garrote JA, Blanco-Quiros A, Calvo C, Fernandez-Salazar L, Del Villar A, Barrera A, Arranz E: Interleukin 18 maintains a long-standing inflammation in coeliac disease patients. Clin Exp Immunol. 2006, 146 (3): 479-485. 10.1111/j.1365-2249.2006.03239.x.
Article
CAS
PubMed
PubMed Central
Google Scholar