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Table 2 Comparison of genotypic frequencies (%) between Coeliac and Control samples (Table 1) and the pooled Coeliac (1 + 2) and Control (1 + 2) samples.

From: Evaluation of 6 candidate genes on chromosome 11q23 for coeliac disease susceptibility: a case control study

   A1A1 A1A2 A2A2 p
Coeliac 1 Vs Control 1      
IL10RA Coeliac 1 86 (23.1) 192 (51.8) 93 (25.1)  
rs2256111 A/G Control 1 69 (19.8) 192 (55.0) 88 (25.2) 0.514
IL10RA Coeliac 1 255 (68.0) 101 (26.9) 19 (5.1)  
rs4252272 A/G Control 1 226 (64.8) 115 (33.0) 8 (2.3) 0.068
IL10RA Coeliac 1 171 (45.4) 169 (44.8) 37 (9.8)  
rs2229113 G/A Control 1 150 (43.7) 167 (48.7) 26 (7.6) 0.426
IL10RA Coeliac 1 113 (30.3) 191 (51.2) 69 (18.5)  
rs9610 G/A Control 1 96 (28.0) 184 (53.6) 63 (18.4) 0.767
CD3E Coeliac 1 118 (33.3) 178 (50.3) 58 (16.4)  
rs3782042 G/A Control 1 133 (39.6) 158 (47.0) 45 (13.4) 0.196
CD3E Coeliac 1 158 (49.7) 131 (41.2) 29 (9.1)  
rs1945764 T/C Control 1 155 (45.9) 160 (47.3) 23 (6.8) 0.223
CD3DG Coeliac 1 193 (54.4) 137 (38.6) 25 (7.0)  
rs2276423 G/C Control 1 171 (49.9) 142 (41.4) 30 (8.8) 0.434
CD3DG Coeliac 1 240 (66.5) 109 (30.2) 12 (3.3)  
rs3181259 G/A Control 1 238 (69.6) 97 (28.4) 7 (2.1) 0.469
CD3DG Coeliac 1 147 (41.9) 159 (45.3) 45 (12.8)  
rs1561966 G/A Control 1 129 (38.2) 170 (50.3) 39 (11.5) 0.422
CD3DG Coeliac 1 187 (52.5) 139 (39.0) 30 (8.4)  
rs7949185 T/C Control 1 183 (53.2) 132 (38.4) 29 (8.4) 0.983
THY1 Coeliac 1 161 (43.5) 171 (46.2) 38 (10.3)  
rs1894006 G/A Control 1 161 (47.1) 155 (45.3) 26 (7.6) 0.380
THY1 Coeliac 1 122 (34.3) 173 (48.6) 61 (17.1)  
rs1001205 G/A Control 1 127 (37.9) 160 (47.8) 48 (14.3) 0.468
IL18 Coeliac 1 145 (44.2) 147 (44.8) 36 (11.0)  
rs2043055 A/G Control 1 116 (38.2) 156 (51.3) 32 (10.5) 0.244
IL18 Coeliac 1 154 (50.3) 135 (44.1) 17 (5.6)  
* -137 rs187238 G/C Control 1 184 (54.6) 121 (35.9) 32 (9.5) 0.038
IL18 Coeliac 1 227 (75.7) 68 (22.7) 5 (1.7)  
rs5744241 A/G Control 1 237 (82.3) 49 (17.0) 2 (0.7) 0.114
IL18 Coeliac 1 138 (36.6) 192 (51.1) 46 (12.2)  
* -607 rs1946518 C/A Control 1 100 (31.1) 153 (47.5) 69 (21.4) 0.005
Coeliac 2 Vs Control 2  
IL18 Coeliac 2 99 (57.9) 56 (32.7) 16 (9.4)  
-137 rs187238 G/C Control 2 272 (52.7) 208 (40.2) 37 (7.1) 0.641
IL18 Coeliac 2 50 (42.4) 48 (40.7) 20 (16.9)  
-607 rs1946518 C/A Control 2 201 (37.5) 256 (47.8) 79 (14.7) 0.712
Coeliac (1 + 2) Vs Controls (1 + 2)    
IL18 Coeliac 253 (53.0) 191 (40.0) 33 (6.9)  
-137 rs187238 G/C Control 456 (53.4) 329 (38.5) 69 (8.1) 0.696
IL18 Coeliac 188 (38.1) 240 (48.6) 66 (13.4)  
-607 rs1946518 C/A Control 301 (35.1) 409 (47.7) 148 (17.2) 0.042
  1. P values (uncorrected for multiple testing) are for genotype heterogeneity (Genepop). SNPs with a reportedly functional role are marked with an asterisk (*).