Osteoporosis prevention, diagnosis, and therapy. Jama. 2001, 285 (6): 785-795. 10.1001/jama.285.6.785.
Marshall D, Johnell O, Wedel H: Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures. Bmj. 1996, 312 (7041): 1254-1259.
Article
CAS
PubMed
PubMed Central
Google Scholar
Cummings SR, Black DM, Nevitt MC, Browner W, Cauley J, Ensrud K, Genant HK, Palermo L, Scott J, Vogt TM: Bone density at various sites for prediction of hip fractures. The Study of Osteoporotic Fractures Research Group. Lancet. 1993, 341 (8837): 72-75. 10.1016/0140-6736(93)92555-8.
Article
CAS
PubMed
Google Scholar
Cranney A, Jamal SA, Tsang JF, Josse RG, Leslie WD: Low bone mineral density and fracture burden in postmenopausal women. Cmaj. 2007, 177 (6): 575-580.
Article
PubMed
PubMed Central
Google Scholar
Yang TL, Chen XD, Guo Y, Lei SF, Wang JT, Zhou Q, Pan F, Chen Y, Zhang ZX, Dong SS, Xu XH, Yan H, Liu X, Qiu C, Zhu XZ, Chen T, Li M, Zhang H, Zhang L, Drees BM, Hamilton JJ, Papasian CJ, Recker RR, Song XP, Cheng J, Deng HW: Genome-wide copy-number-variation study identified a susceptibility gene, UGT2B17, for osteoporosis. Am J Hum Genet. 2008, 83 (6): 663-674. 10.1016/j.ajhg.2008.10.006.
Article
CAS
PubMed
PubMed Central
Google Scholar
Styrkarsdottir U, Halldorsson BV, Gretarsdottir S, Gudbjartsson DF, Walters GB, Ingvarsson T, Jonsdottir T, Saemundsdottir J, Center JR, Nguyen TV, Bagger Y, Gulcher JR, Eisman JA, Christiansen C, Sigurdsson G, Kong A, Thorsteinsdottir U, Stefansson K: Multiple genetic loci for bone mineral density and fractures. N Engl J Med. 2008, 358 (22): 2355-2365. 10.1056/NEJMoa0801197.
Article
CAS
PubMed
Google Scholar
Cheng XG, Lowet G, Boonen S, Nicholson PH, Brys P, Nijs J, Dequeker J: Assessment of the strength of proximal femur in vitro: relationship to femoral bone mineral density and femoral geometry. Bone. 1997, 20 (3): 213-218. 10.1016/S8756-3282(96)00383-3.
Article
CAS
PubMed
Google Scholar
Edmondston SJ, Singer KP, Day RE, Price RI, Breidahl PD: Ex vivo estimation of thoracolumbar vertebral body compressive strength: the relative contributions of bone densitometry and vertebral morphometry. Osteoporos Int. 1997, 7 (2): 142-148. 10.1007/BF01623690.
Article
CAS
PubMed
Google Scholar
Livshits G, Yakovenko K, Kobyliansky E: Quantitative genetic study of radiographic hand bone size and geometry. Bone. 2003, 32 (2): 191-198. 10.1016/S8756-3282(02)00954-7.
Article
CAS
PubMed
Google Scholar
Ahlborg HG, Johnell O, Turner CH, Rannevik G, Karlsson MK: Bone loss and bone size after menopause. N Engl J Med. 2003, 349 (4): 327-334. 10.1056/NEJMoa022464.
Article
PubMed
Google Scholar
Faulkner KG, Cummings SR, Black D, Palermo L, Gluer CC, Genant HK: Simple measurement of femoral geometry predicts hip fracture: the study of osteoporotic fractures. J Bone Miner Res. 1993, 8 (10): 1211-1217. 10.1002/jbmr.5650081008.
Article
CAS
PubMed
Google Scholar
Cummings SR, Cauley JA, Palermo L, Ross PD, Wasnich RD, Black D, Faulkner KG: Racial differences in hip axis lengths might explain racial differences in rates of hip fracture. Study of Osteoporotic Fractures Research Group. Osteoporos Int. 1994, 4 (4): 226-229. 10.1007/BF01623243.
Article
CAS
PubMed
Google Scholar
Rosso R, Minisola S: Hip axis length in an Italian osteoporotic population. Br J Radiol. 2000, 73 (873): 969-972.
Article
CAS
PubMed
Google Scholar
Deng HW, Xu FH, Davies KM, Heaney R, Recker RR: Differences in bone mineral density, bone mineral content, and bone areal size in fracturing and non-fracturing women, and their interrelationships at the spine and hip. J Bone Miner Metab. 2002, 20 (6): 358-366. 10.1007/s007740200052.
Article
CAS
PubMed
Google Scholar
Shen H, Long JR, Xiong DH, Guo YF, Xiao P, Liu YZ, Zhao LJ, Liu YJ, Deng HY, Li JL, Recker RR, Deng HW: A genomewide scan for quantitative trait loci underlying areal bone size variation in 451 Caucasian families. J Med Genet. 2006, 43 (11): 873-880. 10.1136/jmg.2006.041251.
Article
CAS
PubMed
PubMed Central
Google Scholar
Boonen S, Koutri R, Dequeker J, Aerssens J, Lowet G, Nijs J, Verbeke G, Lesaffre E, Geusens P: Measurement of femoral geometry in type I and type II osteoporosis: differences in hip axis length consistent with heterogeneity in the pathogenesis of osteoporotic fractures. J Bone Miner Res. 1995, 10 (12): 1908-1912. 10.1002/jbmr.5650101210.
Article
CAS
PubMed
Google Scholar
Karlsson KM, Sernbo I, Obrant KJ, Redlund-Johnell I, Johnell O: Femoral neck geometry and radiographic signs of osteoporosis as predictors of hip fracture. Bone. 1996, 18 (4): 327-330. 10.1016/8756-3282(96)00004-X.
Article
CAS
PubMed
Google Scholar
Michelotti J, Clark J: Femoral neck length and hip fracture risk. J Bone Miner Res. 1999, 14 (10): 1714-1720. 10.1359/jbmr.1999.14.10.1714.
Article
CAS
PubMed
Google Scholar
Duan Y, Tabensky A, DeLuca V, Seeman E: The benefit of hormone replacement therapy on bone mass is greater at the vertebral body than posterior processes or proximal femur. Bone. 1997, 21 (5): 447-451. 10.1016/S8756-3282(97)00177-4.
Article
CAS
PubMed
Google Scholar
Alonso CG, Curiel MD, Carranza FH, Cano RP, Perez AD: Femoral bone mineral density, neck-shaft angle and mean femoral neck width as predictors of hip fracture in men and women. Multicenter Project for Research in Osteoporosis. Osteoporos Int. 2000, 11 (8): 714-720. 10.1007/s001980070071.
Article
CAS
PubMed
Google Scholar
Seeman E, Delmas PD: Bone quality--the material and structural basis of bone strength and fragility. N Engl J Med. 2006, 354 (21): 2250-2261. 10.1056/NEJMra053077.
Article
CAS
PubMed
Google Scholar
Deng HW, Deng XT, Conway T, Xu FH, Heaney R, Recker RR: Determination of bone size of hip, spine, and wrist in human pedigrees by genetic and lifestyle factors. J Clin Densitom. 2002, 5 (1): 45-56. 10.1385/JCD:5:1:045.
Article
PubMed
Google Scholar
Deng HW, Xu FH, Liu YZ, Shen H, Deng H, Huang QY, Liu YJ, Conway T, Li JL, Davies KM, Recker RR: A whole-genome linkage scan suggests several genomic regions potentially containing QTLs underlying the variation of stature. Am J Med Genet. 2002, 113 (1): 29-39. 10.1002/ajmg.10742.
Article
PubMed
Google Scholar
Jian WX, Long JR, Deng HW: High heritability of bone size at the hip and spine in Chinese. J Hum Genet. 2004, 49 (2): 87-91. 10.1007/s10038-003-0113-4.
Article
PubMed
Google Scholar
Havill LM, Mahaney MC, T LB, Specker BL: Effects of genes, sex, age, and activity on BMC, bone size, and areal and volumetric BMD. J Bone Miner Res. 2007, 22 (5): 737-746. 10.1359/jbmr.070213.
Article
PubMed
Google Scholar
Karasik D, Ginsburg E, Livshits G, Pavlovsky O, Kobyliansky E: Evidence of major gene control of cortical bone loss in humans. Genet Epidemiol. 2000, 19 (4): 410-421. 10.1002/1098-2272(200012)19:4<410::AID-GEPI11>3.0.CO;2-K.
Article
CAS
PubMed
Google Scholar
Cohen Z, Kalichman L, Kobyliansky E, Malkin I, Almog E, Livshits G: Cortical index and size of hand bones: segregation analysis and linkage with the 11q12-13 segment. Med Sci Monit. 2003, 9 (3): MT13-20.
PubMed
Google Scholar
Ginsburg E, Skaric-Juric T, Kobyliansky E, Karasik D, Malkin I, Rudan P: Evidence on major gene control of cortical index in pedigree data from Middle Dalmatia, Croatia. Am J Hum Biol. 2001, 13 (3): 398-408. 10.1002/ajhb.1064.
Article
CAS
PubMed
Google Scholar
Liu PY, Qin YJ, Recker RR, Deng HW: Evidence for a major gene underlying bone size variation in the Chinese. Am J Hum Biol. 2004, 16 (1): 68-77. 10.1002/ajhb.10240.
Article
PubMed
Google Scholar
Fang Y, van Meurs JB, Rivadeneira F, van Schoor NM, van Leeuwen JP, Lips P, Pols HA, Uitterlinden AG: Vitamin D receptor gene haplotype is associated with body height and bone size. J Clin Endocrinol Metab. 2007, 92 (4): 1491-1501. 10.1210/jc.2006-1134.
Article
CAS
PubMed
Google Scholar
Lei SF, Deng FY, Xiao SM, Chen XD, Deng HW: Association and haplotype analyses of the COL1A2 and ER-alpha gene polymorphisms with bone size and height in Chinese. Bone. 2005, 36 (3): 533-541. 10.1016/j.bone.2004.11.002.
Article
CAS
PubMed
Google Scholar
Zmuda JM, Cauley JA, Kuller LH, Ferrell RE: A common promotor variant in the cytochrome P450c17alpha (CYP17) gene is associated with bioavailability testosterone levels and bone size in men. J Bone Miner Res. 2001, 16 (5): 911-917. 10.1359/jbmr.2001.16.5.911.
Article
CAS
PubMed
Google Scholar
Raisz LG: Pathogenesis of osteoporosis: concepts, conflicts, and prospects. J Clin Invest. 2005, 115 (12): 3318-3325. 10.1172/JCI27071.
Article
CAS
PubMed
PubMed Central
Google Scholar
Liu YZ, Wilson SG, Wang L, Liu XG, Guo YF, Li J, Yan H, Deloukas P, Soranzo N, Chinnapen-Horsley U, Cervino A, Williams FM, Xiong DH, Zhang YP, Jin TB, Levy S, Papasian CJ, Drees BM, Hamilton JJ, Recker RR, Spector TD, Deng HW: Identification of PLCL1 gene for hip bone size variation in females in a genome-wide association study. PLoS ONE. 2008, 3 (9): e3160-10.1371/journal.pone.0003160.
Article
PubMed
PubMed Central
Google Scholar
Lin X, Varnai P, Csordas G, Balla A, Nagai T, Miyawaki A, Balla T, Hajnoczky G: Control of calcium signal propagation to the mitochondria by inositol 1,4,5-trisphosphate-binding proteins. J Biol Chem. 2005, 280 (13): 12820-12832. 10.1074/jbc.M411591200.
Article
CAS
PubMed
Google Scholar
Riddle RC, Taylor AF, Genetos DC, Donahue HJ: MAP kinase and calcium signaling mediate fluid flow-induced human mesenchymal stem cell proliferation. Am J Physiol Cell Physiol. 2006, 290 (3): C776-784. 10.1152/ajpcell.00082.2005.
Article
CAS
PubMed
Google Scholar
Reich KM, Frangos JA: Effect of flow on prostaglandin E2 and inositol trisphosphate levels in osteoblasts. Am J Physiol. 1991, 261 (3 Pt 1): C428-432.
CAS
PubMed
Google Scholar
Bagger YZ, Tanko LB, Alexandersen P, Qin G, Christiansen C: Radiographic measure of aorta calcification is a site-specific predictor of bone loss and fracture risk at the hip. J Intern Med. 2006, 259 (6): 598-605. 10.1111/j.1365-2796.2006.01640.x.
Article
CAS
PubMed
Google Scholar
Bagger YZ, Tanko LB, Alexandersen P, Hansen HB, Qin G, Christiansen C: The long-term predictive value of bone mineral density measurements for fracture risk is independent of the site of measurement and the age at diagnosis: results from the Prospective Epidemiological Risk Factors study. Osteoporos Int. 2006, 17 (3): 471-477. 10.1007/s00198-005-0009-6.
Article
PubMed
Google Scholar
Fairbrother UL, Tanko LB, Walley AJ, Christiansen C, Froguel P, Blakemore AI: Leptin receptor genotype at Gln223Arg is associated with body composition, BMD, and vertebral fracture in postmenopausal Danish women. J Bone Miner Res. 2007, 22 (4): 544-550. 10.1359/jbmr.070114.
Article
CAS
PubMed
Google Scholar
Szulc P, Seeman E, Duboeuf F, Sornay-Rendu E, Delmas PD: Bone fragility: failure of periosteal apposition to compensate for increased endocortical resorption in postmenopausal women. J Bone Miner Res. 2006, 21 (12): 1856-1863. 10.1359/jbmr.060904.
Article
PubMed
Google Scholar
Valimaki MJ, Tahtela R, Jones JD, Peterson JM, Riggs BL: Bone resorption in healthy and osteoporotic postmenopausal women: comparison markers for serum carboxy-terminal telopeptide of type I collagen and urinary pyridinium cross-links. Eur J Endocrinol. 1994, 131 (3): 258-262. 10.1530/eje.0.1310258.
Article
CAS
PubMed
Google Scholar
Kushida K, Takahashi M, Kawana K, Inoue T: Comparison of markers for bone formation and resorption in premenopausal and postmenopausal subjects, and osteoporosis patients. J Clin Endocrinol Metab. 1995, 80 (8): 2447-2450. 10.1210/jc.80.8.2447.
CAS
PubMed
Google Scholar
Eastell R, Hannon RA: Biomarkers of bone health and osteoporosis risk. Proc Nutr Soc. 2008, 67 (2): 157-162. 10.1017/S002966510800699X.
Article
PubMed
Google Scholar
Chavassieux P, Chenu C, Valentin-Opran A, Delmas PD, Boivin G, Chapuy MC, Meunier PJ: In vitro exposure to sodium fluoride does not modify activity or proliferation of human osteoblastic cells in primary cultures. J Bone Miner Res. 1993, 8 (1): 37-44. 10.1002/jbmr.5650080106.
Article
CAS
PubMed
Google Scholar
Pietschmann P, Resch H, Krexner E, Woloszczuk W, Willvonseder R: Decreased serum osteocalcin levels in patients with postmenopausal osteoporosis. Acta Med Austriaca. 1991, 18 (5): 114-116.
CAS
PubMed
Google Scholar
Einhorn TA, Wakley GK, Linkhart S, Rush EB, Maloney S, Faierman E, Baylink DJ: Incorporation of sodium fluoride into cortical bone does not impair the mechanical properties of the appendicular skeleton in rats. Calcif Tissue Int. 1992, 51 (2): 127-131. 10.1007/BF00298500.
Article
CAS
PubMed
Google Scholar
Farley SM, Wergedal JE, Farley JR, Javier GN, Schulz EE, Talbot JR, Libanati CR, Lindegren L, Bock M, Goette MM, et al: Spinal fractures during fluoride therapy for osteoporosis: relationship to spinal bone density. Osteoporos Int. 1992, 2 (5): 213-218. 10.1007/BF01624143.
Article
CAS
PubMed
Google Scholar
Hodsman AB, Drost DJ: The response of vertebral bone mineral density during the treatment of osteoporosis with sodium fluoride. J Clin Endocrinol Metab. 1989, 69 (5): 932-938. 10.1210/jcem-69-5-932.
Article
CAS
PubMed
Google Scholar
Guanabens N, Pares A, del Rio L, Roca M, Gomez R, Munoz J, Rodes J: Sodium fluoride prevents bone loss in primary biliary cirrhosis. J Hepatol. 1992, 15 (3): 345-349. 10.1016/0168-8278(92)90066-X.
Article
CAS
PubMed
Google Scholar
Leeming DJ, Henriksen K, Byrjalsen I, Qvist P, Madsen SH, Garnero P, Karsdal MA: Is bone quality associated with collagen age?. Osteoporos Int. 2009, 20 (9): 1461-1470. 10.1007/s00198-009-0904-3.
Article
CAS
PubMed
Google Scholar