SLC1A3 C3590T but not BDNF G196A is a predisposition factor for stress as well as depression, in an adolescent eastern Indian population

Table 3 Genotypic distribution of SLC1A3 C3590T (rs 2,269,272) in relation with Stress and Depression

Genotype/Allele frequency	Cases (N = 108)	Controls (N = 205)	p (χ²)	Odds ratio (OR)	95% Confidence Interval (CI)
CC	50 (46.3%)	130 (63.4%)	0.0115 (8.934)*
CT	55 (50.9%)	69 (33.7%)
TT	3 (2.8%)	6 (2.9%)
Linear by linear association (Armitage tests for trends)			0.010*
Dominant Model (CT + TT vs. CC)			0.0052 (7.796)*	2.011	1.25–3.23
Co- dominant Model (CT vs. CC)			0.0042 (8.205)*	2.072	1.28–3.35
Recessive Model (TT vs. CT + CC)			1.0000	0.948	0.23–3.87
Additive Model (TT vs. CC)			0.7122	1.300	0.31–5.40
Allele frequency distribution
Alleles	Cases	Controls	p (χ²)
C	155 (0.72)	329 (0.80)	0.0159 (5.807)*
T	61 (0.28)	81 (0.20)

The table represents the genotypic frequency, the allelic frequency as well as odds - ratio for different models. Number of participants (n) = 313
* indicates p < 0.05

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