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Table 5 Association between various related factors and gastric mucosal erosion in patients taking aspirin

From: Increased risk of aspirin-induced gastric mucosal erosion in elderly Chinese men harboring SLCO1B1*1b/*1b while using aspirin and an ACEI or ARB concomitantly

 Mantel-Haenszel OR (95% CI)Adjusted OR (95% CI)
Age, yrs 1.33 (1.04–2.87)*
Creatinine 1.77 (0.62–3.48)
eGFR 8.04 (3.02–22.6)**
History of gastric ulcers2.74 (1.12–6.72)*2.41 (1.08–5.01)*
Diabetes mellitus2.16 (1.23–3.67) **1.44 (0.87–2.39)
PPIs0.22 (0.13–0.38)***0.18 (0.11–0.31)***
SLCO1B1*1b/*1b2.29 (1.35–3.88)**2.64 (1.59–4.17)*
SLCO1B1*15/*150.10 (0.01–0.84)*0.26 (0.08–1.31)
SLCO1B1*1a/*150.25 (0.09–0.70)**0.77 (0.36–2.95)
  1. The unadjusted OR and 95% CI were obtained by Mantel–Haenszel statistics, and the adjusted OR and 95% CI were obtained by multiple logistic regression analysis after adjustment for other factors. * p < 0.05. ** p < 0.01. *** p < 0.001
  2. Abbreviations: eGFR Estimated glomerular filtration rate, PPIs Proton-pump inhibitors