First author | Year | Country | Age group | Type of case | Type of control | Ethnicity | Case | Control | HWEa in control | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
GG | GC | CC | GG | GC | CC | ||||||||
Schluter B | 2002 | USA | Adult | Sepsis, severe sepsis | Healthy | Caucasian | 25 | 46 | 24 | 71 | 94 | 42 | Yes |
Non-survivor | Survivor | 2 | 17 | 6 | 11 | 8 | 6 | Yes | |||||
Harding D | 2003 | UK | Infant | Septicemia | Preterm infant | Mainly Caucasian | 24 | 27b | 30 | 76b | N/A | ||
Balding J | 2003 | Ireland | Adult | Meningococcal sepsis | Healthy | Caucasian | 59 | 97 | 27 | 123 | 209 | 68 | Yes |
Non-survivor | Survivor | 13 | 10 | 2 | 46 | 87 | 25 | Yes | |||||
Treszl A | 2003 | Hungary | Neonate | Sepsis | VLBWc neonate | Caucasian | 18 | 13 | 2 | 34 | 29 | 7 | Yes |
Barber RC | 2004 | USA | Adult | Severe sepsis | ICU patients with no or mild sepsis | Mixed | 17 | 19b | 69 | 54b | N/A | ||
Ahrens P | 2004 | Germany | Infant | Sepsis | VLBWc infants | Caucasian | 24 | 21 | 5 | 97 | 177 | 32 | No |
Michalek J | 2006 | Czech Republic | aged 0–19 years | SIRSd, sepsis, severe sepsis, septic shock and MODSe | Healthy | Caucasian | 103 | 172 | 48 | 160 | 345 | 139 | Yes |
McDaniel DO | 2006 | USA | not clearf | Sepsis | ICU patients | African American | 16g | 0 | 6g | 0 | N/A | ||
Caucasian | 12g | 3 | 13g | 8 | N/A | ||||||||
Sipahi T | 2006 | Turkey | aged 0–15 years | Severe sepsis | Healthy | not clear | 26 | 14 | 4 | 52 | 19 | 6 | No |
Non-survivor | Survivor | 9 | 5 | 1 | 17 | 9 | 3 | Yes | |||||
Baier RJ | 2006 | USA | Infant | Sepsis | VLBWc infant | African American | 94 | 18 | 2 | 110 | 9 | 0 | Yes |
Caucasian | 12 | 16 | 3 | 7 | 16 | 3 | Yes | ||||||
Non-survivor | Survivor | African American | 10 | 1 | 0 | 84 | 17 | 2 | Yes | ||||
Caucasian | 1 | 1 | 1 | 11 | 15 | 2 | Yes | ||||||
Göpel W | 2006 | Germany | Infant | Sepsis | VLBWc infant | Mainly Caucasian | 29 | 50 | 18 | 128 | 143 | 49 | Yes |
Sabeinikovs O | 2008 | Latvia | Infant | Non-survivor | Survivor | Caucasian | 10 | 21 | 13 | 20 | 32 | 7 | Yes |
Abdel-Hady H | 2009 | Egypt | Neonate | Sepsis | Neonates investigated for neonatal hyperbilirubinemia | Caucasian | 17 | 26 | 11 | 28 | 32 | 11 | Yes |
Non-survivor | Survivor | 2 | 5 | 6 | 15 | 21 | 5 | Yes | |||||
Solé-Violán J | 2010 | Spain | Adult | Severe sepsis and septic shock | CAPh | Caucasian | 141 | 144 | 36 | 392 | 341 | 84 | Yes |
Davis SM | 2010 | USA | Female adult | Puerperal group streptococcus sepsis | Healthy | Caucasian | 10 | 11 | 2 | 21 | 22 | 9 | Yes |
Carregaro F | 2011 | Brazil | Adult | Sepsis, severe sepsis and septic shock | Healthy | Mainly Caucasiani | 49 | 39 | 9 | 94 | 96 | 17 | Yes |
Accardo Palumbo A | 2011 | Italy | aged 13–82 years | Sepsis | Burned patient | not clear | 14g | 2 | 22g | 4 | N/A | ||
Watanabe E | 2012 | USA | Adult | Non-survivor | Survivor | Caucasian | 113 | 149 | 46 | 245 | 363 | 125 | Yes |
MartÃn-Loeches I | 2012 | Spain | Adult | Sepsis, severe sepsis and septic shock | Healthy | Caucasian | 581 | 516 | 130 | 438 | 413 | 102 | Yes |
Feng B | 2015 | China | Adult | Non-survivor | Survivor | Asian | 42 | 20 | 1 | 139 | 72 | 3 | Yes |
Allam G | 2015 | Saudi Arabia | Infant | Early-onset sepsis | Healthy | not clear | 39 | 20 | 10 | 13 | 32 | 23 | Yes |
Lorente L | 2016 | Spain | Adult | Non-survivor | Survivor | not clear | 47 | 36 | 3 | 76 | 74 | 27 | Yes |
Mao ZR | 2016 | China | Adult | Sepsis | Healthy | Asian | 56 | 37 | 95 | 97 | 66 | 37 | No |
Jimenez-Sousa MA | 2017 | Spain | Adult | Septic shock | Healthy | Not clear | 93 | 90 | 19 | 43 | 51 | 13 | Yes |