Stage 1 samples (discovery panel) | Cases (n = 372) | Controls (n = 360) |
---|---|---|
Gender (M/F) | 188/184 | 148/212 |
Age | 64.4 ± 10.3 | 46.3 ± 19.9 |
HbA1C (%) | 7.39 ± 1.48 | 4.79 ± 0.36 |
BMI (kg/m2) | 23.7 ± 3.5 | 22.0 ± 2.9 |
Age at onset < 50 (%) | 175 (47.0) | - |
≥50(%) | 195 (52.5) | - |
unknown (%) | 2 (0.5) | - |
Family history (%) | 125 (33.6) | - |
   Diabetes in both parents | 11 |  |
   Diabetes in one parent | 110 |  |
   Diabetes in son or daughter | 4 |  |
Insulin therapy (+) (%) | 112 (30.1) | - |
Stage 2 samples (replication panel) | Cases (n = 532) | Controls (n = 530) |
Gender (M/F) | 246/286 | 284/246 |
Age | 62.0 ± 10.7 | 37.8 ± 11.3 |
HbA1C (%) | 7.47 ± 1.43 | 4.88 ± 0.33 |
BMI (kg/m2) | 23.6 ± 3.3 | 22.4 ± 3.0 |
Age at onset < 50 (%) | 244 (45.9) | - |
≥50(%) | 287 (53.9) | - |
unknown (%) | 1 (0.2) | - |
Family history (%) | 207 (38.9) | - |
   Diabetes in both parents | 22 |  |
   Diabetes in one parent | 180 |  |
   Diabetes in son or daughter | 5 |  |
Insulin therapy (+) (%) | 172 (32.3) | - |
Stage 1 + Stage 2 combined samples | Cases (n = 904) | Controls (n = 890) |
Gender (M/F) | 434/470 | 432/458 |
Age | 63.0 ± 10.6 | 41.2 ± 15.9 |
HbA1C (%) | 7.43 ± 1.45 | 4.84 ± 0.34 |
BMI (kg/m2) | 23.6 ± 3.4 | 22.3 ± 3.0 |
Age at onset < 50 (%) | 419 (46.4) | - |
≥50(%) | 482 (53.3) | - |
unknown (%) | 3 (0.3) | - |
Family history (%) | 332 (36.7) | - |
   Diabetes in both parents | 33 |  |
   Diabetes in one parent | 290 |  |
   Diabetes in son or daughter | 9 |  |
Insulin therapy (+) (%) | 284 (31.4) | - |