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Table 2 Characteristics of the 1,794 Japanese subjects used in the association tests

From: Lack of association of genetic variation in chromosome region 15q14-22.1 with type 2 diabetes in a Japanese population

Stage 1 samples (discovery panel) Cases (n = 372) Controls (n = 360)
Gender (M/F) 188/184 148/212
Age 64.4 ± 10.3 46.3 ± 19.9
HbA1C (%) 7.39 ± 1.48 4.79 ± 0.36
BMI (kg/m2) 23.7 ± 3.5 22.0 ± 2.9
Age at onset < 50 (%) 175 (47.0) -
≥50(%) 195 (52.5) -
unknown (%) 2 (0.5) -
Family history (%) 125 (33.6) -
   Diabetes in both parents 11  
   Diabetes in one parent 110  
   Diabetes in son or daughter 4  
Insulin therapy (+) (%) 112 (30.1) -
Stage 2 samples (replication panel) Cases (n = 532) Controls (n = 530)
Gender (M/F) 246/286 284/246
Age 62.0 ± 10.7 37.8 ± 11.3
HbA1C (%) 7.47 ± 1.43 4.88 ± 0.33
BMI (kg/m2) 23.6 ± 3.3 22.4 ± 3.0
Age at onset < 50 (%) 244 (45.9) -
≥50(%) 287 (53.9) -
unknown (%) 1 (0.2) -
Family history (%) 207 (38.9) -
   Diabetes in both parents 22  
   Diabetes in one parent 180  
   Diabetes in son or daughter 5  
Insulin therapy (+) (%) 172 (32.3) -
Stage 1 + Stage 2 combined samples Cases (n = 904) Controls (n = 890)
Gender (M/F) 434/470 432/458
Age 63.0 ± 10.6 41.2 ± 15.9
HbA1C (%) 7.43 ± 1.45 4.84 ± 0.34
BMI (kg/m2) 23.6 ± 3.4 22.3 ± 3.0
Age at onset < 50 (%) 419 (46.4) -
≥50(%) 482 (53.3) -
unknown (%) 3 (0.3) -
Family history (%) 332 (36.7) -
   Diabetes in both parents 33  
   Diabetes in one parent 290  
   Diabetes in son or daughter 9  
Insulin therapy (+) (%) 284 (31.4) -