Table 3 Multiple linear regression analysis of relationships between mtDNA content and age, metastasis status and stage of cancer in tumor and non-tumor tissues in patients with or without the 4,977 bp mtDNA deletion
mtDNA content | Â | Patients without 4977 bp deletion | Patients with 4977 bp deletion | ||||
|---|---|---|---|---|---|---|---|
| Â | Characteristics | Coefficients (B) | 95% CI for B | p-value | Coefficients (B) | 95% CI for B | p-value |
Non-tumor | Age | 0.191 | -0.220 to 0.602 | 0.333 | 0.027 | -0.055 to 0.108 | 0.493 |
| Â | LN metastasis | 25.029 | -0.328 to 50.386 | 0.053 | 2.137 | -1.464 to 5.739 | 0.224 |
| Â | Stage | 14.460 | -1.759 to 30.679 | 0.076 | 1.690 | -0.614 to 3.993 | 0.138 |
Tumor | Age | 0.017 | -0.052 to 0.087 | 0.602 | 0.064 | -0.033 to 0.161 | 0.180 |
| Â | LN metastasis | -0.330 | -4.619 to 3.959 | 0.871 | 7.880 | 3.578 to 12.182 | 0.002* |
| Â | Stage | -0.100 | -2.844 to 2.643 | 0.938 | 5.839 | 3.088 to 8.590 | 0.000* |