Figure 4

Comparison of mtDNA content between tumor and non-tumor tissues. mtDNA content in tumor (closed circle) and non-tumor (open circle) tissues are compared in patients (A) carrying the mtDNA 4,977-bp deletion in both tissues (B) carrying the mtDNA 4,977-bp deletion only in tumor tissues, (C) carrying the mtDNA 4,977-bp deletion only in non-tumor tissues, and (D) age and gender matched patients without the deletion. All p values were derived from paired-samples T test analysis.