From: Genotype-phenotype correlations among BRCA14153delA and 5382insC mutation carriers from Latvia
Variable | c.4034delA | c.5266dupC | Control |
---|---|---|---|
N. of patients | 25 | 68 | 103 |
Median age of onset (years) | 51.7 | 46.5 | 54.9 |
T4 - n. (%) | 5 (20%) | 10 (15%) | 7 (7%) |
T3 - n. (%) | 1 (4%) | 3 (4%) | 13 (13%) |
T2 - n. (%) | 14 (56%) | 43 (63%) | 63 (61%) |
T1 - n. (%) | 5 (20%) | 12 (18%) | 20 (19%) |
Axillary node positive - n. (%) | 14 (56%) | 32 (47%) | 44 (43%) |
ER/PR positive (%) | 50% | 15% | 70% |
HER2 positive (%) | 22% | 11% | 10% |
ER/PR/HER2 (Triple) negative (%) | 50% | 79% | 24% |
N. of patients dead from cancer during follow-up period | 9 (36%) | 15 (22%) | 21 (20%) |