| chronic anovulation | hirsutism-score [F/G] > 7 hirsutism-score [F/G] | alopecia | acne | PCO | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
gene (SNP) minor allele | OR | 95% CI | p | OR β | 95% CI | p | OR | 95% CI | p | OR | 95% CI | p | OR | 95% CI | p |
FTO (rs9939609) A | 1.29 | (0.70;2.37) | 0.41 | 1.15 0.34 | (0.87;1.54) (0,59;1.28) | 0.33 0.47 | 0.90 | (0.65;1.24) | 0.50 | 0.97 | (0.73;1.30) | 0.85 | 0.57 | (0.36;0.88) | 0.01 |
INSIG2 (rs7566605) C | 1.02 | (0.54;1.90) | 0.96 | 1.03 -0.08 | (0.76;1.38) (1.06;0.90) | 0.87 0.87 | 1.17 | (0.83;1.64) | 0.37 | 1.00 | (0.74;1.35) | 0.99 | 1.02 | (0.65;1.60) | 0.93 |
TCF7L2 (rs7903146) T | 0.64 | (0.35;1.18) | 0.15 | 0.88 0.09 | (0.64;1.21) (0.95;1.12) | 0.44 0.87 | 0.75 | (0.51;1.08) | 0.12 | 0.84 | (0.61;1.15) | 0.28 | 0.77 | (0.48;1.21) | 0.25 |
MC4R (rs2229616) T | - | - | - | 1.73 -0.39 | (0.51;5.84) (4.16;3.38) | 0.38 0.84 | 0.91 | (0.24;3.46) | 0.89 | 0.54 | (0.16;1.82) | 0.32 | 1.48 | (0.18;12.50) | 0.71 |
MC4R (rs17782313) C | 1.01 | (0.52;1.95) | 0.98 | 0.85 0.16 | (0.62;1.17) (0.88;1.21) | 0.33 0.76 | 1.01 | (0.70;1.44) | 0.98 | 1.04 | (0.76;1.43) | 0.81 | 0.95 | (0.59;1.52) | 0.82 |
MC4R (rs12970134) A | 0.74 | (0.39;1.39) | 0.34 | 0.97 0.40 | (0.71;1.32) (0.60;1.41) | 0.83 0.43 | 1.09 | (0.77;1.54) | 0.62 | 1.06 | (0.78;1.45) | 0.70 | 1.03 | (0.64;1.64) | 0.71 |