Figure 1
![Figure 1](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2F1471-2350-10-57/MediaObjects/12881_2008_Article_471_Fig1_HTML.jpg)
cDNA analysis of the APC exon 4 deletion confirming the results obtained by MLPA. A. forward reference sequence; B. forward sequence with exon 4 deletion; C. reverse reference sequence; D. reverse sequence with exon 4 deletion; E. Nucleotidic and aminoacidic sequences showing the effect of the exon 4 deletion, which results in a frameshift that creates a stop codon at residue 442.