Glutathione S-transferase M1 and T1 genes deletion polymorphisms and risk of developing essential hypertension: a case-control study in Burkina Faso population (West Africa)

Table 1 General Characteristics of the study population

Parameters	Total, n (%) 514 (100%)	Cases, n (%) 245 (100%)	Controls, n (%) 269 (100%)	p value
Gender (M/F)	240/274	111/134	129/140	0.59
Age (years)	49.38 ± 8.90	50.14 ± 8.22	48.69 ± 9.43	0.06
SBP (mmHg)	139.27 ± 30.32	166.24 ± 19.92	114.71 ± 11.35	< 0.001*
DBP (mmHg)	83.77 ± 16.56	97.28 ± 12.09	71.47 ± 8.55	< 0.001*
BMI (Kg/m²)	25.98 ± 6.19	28.35 ± 6.40	23.82 ± 5.11	< 0.001*
WC (cm)	90.28 ± 12.21	96.28 ± 12.26	84.81 ± 9.25	< 0.001*
Fasting Blood Glucose (mM)	5.15 ± 1.81	5.69 ± 1.56	3.75 ± 1.69	< 0.001*
HDL-c (mM)	1.31 ± 0.60	1.40 ± 0.63	1.07 ± 0.42	0.001*
LDL-c (mM)	2.90 ± 1.12	3.02 ± 1.09	2.61 ± 1.14	0.04*
Total Cholesterol (mM)	4.90 ± 1.29	5.10 ± 1.18	4.38 ± 1.44	0.001*
Triglycerides (mM)	1.18 ± 0.75	1.25 ± 0.77	1.00 ± 0.65	0.51
Creatinine (μM)	98.40 ± 23.82	96.80 ± 25.54	106.10 ± 10.38	0.26
Calcium (mM)	2.54 ± 1.04	2.51 ± 1.09	2.68 ± 0.83	0.63
Magnesium (mM)	0.79 ± 0.29	0.81 ± 0.31	0. 69 ± 0.11	0.22
Sodium (mM)	140.46 ± 5.47	139.98 ± 5.38	142.54 ± 5.62	0.16
Potassium (mM)	4.16 ± 0.82	4.01 ± 0.71	4.80 ± 1.00	0.03*
Chlorine (mM)	102.78 ± 5.99	102.24 ± 5.64	105.17 ± 7.14	0.14

Values are reported as means ± standard deviation for continuous variables; Statistical analysis (Cases versus controls) by t test or chi-square; *: significant difference between groups (p < 0.05); MD Means difference, CI Confidence interval, SBP Systolic blood pressure, DBP Diastolic blood pressure, WC Waist circumference, HDL-c High density lipoprotein cholesterol, LDL-c Low density lipoprotein cholesterol, mM Millimolar, μM Micromolar

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