Table 1 Distribution of alleles and genotypes of IL-10 SNPs

-592 (rs1800872)

n

A

C

p-Value

AA

AC

CC

AA vs. AC + CC

OR (95% CI)

 PEX, n (%)

114

130 (57.02)

98 (42.98)

0.39

16 (14)

98 (86)

0 (0)

0.04

4.97 (4.45–21.08)

 PEXG, n (%)

118

128 (54.24)

108 (45.76)

0.68

10 (8.5)

108 (91.5)

0 (0)

0.26

NA

 POAG, n (%)

114

126 (55.26)

102 (44.74)

0.57

12 (10.5)

102 (89.5)

0 (0)

0.14

NA

 Control, n (%)

126

130 (51.59)

122 (48.41)

Ref group

4 (3.2)

122 (96.8)

0 (0)

Ref group

–

-819 (rs1800871)

n

T

C

p-Value

TT

TC

CC

TT vs. TC + CC

OR (95% CI)

 PEX, n (%)

114

130 (57.02)

98 (42.98)

0.39

16 (14)

98 (86)

0 (0)

0.004

10.12 (13.29–71.61)

 PEXG, n (%)

118

128 (54.24)

108 (45.76)

0.68

10 (8.5)

108 (91.5)

0 (0)

0.03

5.74 (7.98–43.34)

 POAG, n (%)

114

126 (55.26)

102 (44.74)

0.57

12 (10.5)

102 (89.5)

0 (0)

0.01

7.29 (9.89–53.53)

 Control, n (%)

126

126 (50)

126 (50)

Ref group

2 (1.6)

122 (96.8)

2 (1.6)

Ref group

–

-1082 (rs1800896)

n

A

G

p-Value

AA

AG

GG

AA vs. AG + GG

OR (95% CI)

 PEX, n (%)

114

132 (57.89)

96 (42.11)

0.22

22 (19.3)

88 (77.2)

4 (3.5)

0.02

7.29 (6.37–29.69)

 PEXG, n (%)

118

130 (55.08)

106 (44.92)

0.43

24 (20.3)

82 (69.5)

12 (10.2)

0.002

7.79 (6.76–31.39)

 POAG, n (%)

114

130 (57.02)

98 (42.98)

0.28

24 (21.1)

82 (71.9)

8 (7)

0.005

8.13 (7.06–32.82)

 Control, n (%)

126

126 (50)

126 (50)

Ref group

4 (3.2)

118 (93.6)

4 (3.2)

Ref group

–