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Table 8 The indexes of the synergistic effect between the dominant model, recessive model and risk factors

From: Analysis on the polymorphisms of site RS4977574, and RS1333045 in region 9p21 and the susceptibility of coronary heart disease in Chinese population

 SAPAPaRERI
Variables- Dominant model of rs4977574
Age- AA/AG + GG3.340.400.700.913
Gender- AA/AG + GG1.63−0.110.39− 0.085
Smoke- AA/AG + GG0.75−0.18−0.33− 0.406
Drink- AA/AG + GG0.56−0.35−0.80− 0.639
Hypertension- AA/AG + GG0.77−0.18−0.31− 0.455
CKMB- AA/AG + GG1.830.380.452.298
HDL- AA/AG + GG0.02−0.30−48.24− 0.305
Glu- AA/AG + GG1.030.020.030.098
Cre- AA/AG + GG1.910.280.480.691
Variables- Recessive model of rs4977574
Age- GG/AG + AA0.25−0.25−2.96−0.273
Gender- GG/AG + AA0.92−0.18−0.090.060
Smoke- GG/AG + AA0.00−0.62− 830.35− 0.618
Drink- GG/AG + AA0.220.47−3.450.417
Hypertension- GG/AG + AA−0.00− 0.19637.34− 0.186
CKMB- GG/AG + AA1.230.120.190.316
HDL- GG/AG + AA0.670.73−0.500.297
Glu- GG/AG + AA−19.620.451.050.779
Cre- GG/AG + AA0.16−0.63−5.19−0.715
Variables- Dominant model of rs1333045
Age- CC/TC + TT0.24−0.76−3.18−1.007
Gender- CC/TC + TT0.820.38−0.220.140
Smoke- CC/TC + TT0.11−0.49−7.75− 0.524
Drink- CC/TC + TT0.090.42−10.570.406
Hypertension- CC/TC + TT0.24−0.37−3.17− 0.414
CKMB- CC/TC + TT1.00−0.00− 0.00− 0.003
HDL- CC/TC + TT0.571.16−0.760.459
Glu- CC/TC + TT−54.490.501.020.967
Cre- CC/TC + TT0.23−0.65−3.34− 0.808
Variables- Recessive model of rs1333045
Age- TT/TC + CC1.850.230.460.479
Gender- TT/TC + CC0.820.11−0.220.075
Smoke- TT/TC + CC0.65−0.27−0.54− 0.529
Drink- TT/TC + CC0.30−0.81−2.33−1.230
Hypertension- TT/TC + CC0.85−0.09−0.17− 0.180
CKMB- TT/TC + CC1.860.380.462.097
HDL- TT/TC + CC−2.37−0.231.42−0.199
Glu- TT/TC + CC0.89−0.09−0.13− 0.339
Cre- TT/TC + CC1.00−0.00−0.00− 0.002
  1. S The synergy index S, AP Attributable proportion of interaction, APa Attributable proportion of pure interaction, RERI Relative excess risk of interaction