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Table 3 Comparisons of serological biomarkers in the dominant model and recessive model

From: Analysis on the polymorphisms of site RS4977574, and RS1333045 in region 9p21 and the susceptibility of coronary heart disease in Chinese population

Dominant model of RS4977574AAAG + GGStatistical parameterP value
CKMB (U/L)16 (12.1–21)17 (13–22)− 1.9250.054
TC (mmol/L)4.64 (3.75–5.61)4.62 (3.92–5.43)− 0.2670.789
TG (mmol/L)1.68 (1.13–2.43)1.82 (1.25–2.49)− 1.7610.078
HDL (mmol/L)1.41 (1.15–1.67)1.36 (1.12–1.62)−1.0590.290
LDL (mmol/L)2.71 (2.14–3.53)2.79 (2.22–3.42)−0.6580.510
ApoA (g/L)1.30 (1.16–1.46)1.29 (1.14–1.46)−1.0380.299
ApoB (g/L)0.91 ± 0.240.92 ± 0.220.5470.585
Glu (mmol/L)5.09 (4.59–6.07)5.07 (4.62–5.90)− 0.0750.940
Bun (mmol/L)4.94 (3.96–5.80)4.87 (4.06–5.88)− 0.1500.881
Cre (μmol/L)70 (62–79.75)71 (62–82)−0.5470.584
Recessive model of RS4977574GGAA+AGStatistical parameterP value
CKMB (U/L)17 (13–22)17 (13–21)−0.2810.779
TC (mmol/L)4.61 (3.93–5.48)4.63 (3.88–5.48)−0.3060.760
TG (mmol/L)1.85 (1.26–2.41)1.75 (1.20–2.50)−1.0600.289
HDL (mmol/L)1.32 (1.10–1.62)1.38 (1.15–1.64)− 1.6970.090
LDL (mmol/L)2.83 (2.26–3.45)2.74 (2.15–3.43)−1.3480.187
ApoA (g/L)1.27 (1.13–1.42)1.30 (1.16–1.48)−2.1910.028
ApoB (g/L)0.90 ± 0.210.92 ± 0.23−1.1680.243
Glu (mmol/L)5.04 (4.55–5.80)5.07 (4.62–6.03)−1.0720.284
Bun (mmol/L)4.87 (4.02–5.61)4.89 (4.06–5.94)−1.3490.177
Cre (μmol/L)69 (61–81)71 (62–81)−1.4690.142
Dominant model of RS1333045CCTC + TTStatistical parameterP value
CKMB (U/L)17 (13–22)16 (13–21)−0.6280.530
TC (mmol/L)4.62 (3.91–5.51)4.63 (3.88–5.48)− 0.3720.710
TG (mmol/L)1.90 (1.27–2.47)1.73 (1.18–2.48)− 1.8070.071
HDL (mmol/L)1.32 (1.11–1.62)1.38 (1.14–1.64)−1.4690.142
LDL (mmol/L)2.94 (2.27–3.51)2.73 (2.14–3.40)−2.1470.032
ApoA (g/L)1.27 (1.13–1.43)1.30 (1.16–1.48)−1.9700.049
ApoB (g/L)0.90 ± 0.210.92 ± 0.23−0.9890.323
Glu (mmol/L)5.07 (4.57–5.79)5.07 (4.62–6.03)−0.9150.360
Bun (mmol/L)4.93 (4.04–5.78)4.87 (4.06–5.90)−0.6120.541
Cre (μmol/L)69 (61–81)71 (62–81)−1.1750.240
Recessive model of RS1333045TTTC + CCStatistical parameterP value
CKMB (U/L)16 (12.4–21)17 (13–21.48)−1.2520.210
TC (mmol/L)4.60 (3.74–5.62)4.65 (3.92–5.44)− 0.1590.873
TG (mmol/L)1.71 (1.15–2.46)1.81 (1.24–2.48)− 1.1310.258
HDL (mmol/L)1.38 (1.13–1.67)1.36 (1.12–1.62)− 0.6410.521
LDL (mmol/L)2.64 (2.09–3.48)2.79 (2.22–3.43)−1.2200.223
ApoA (g/L)1.29 (1.15–1.46)1.29 (1.14–1.46)−0.2330.816
ApoB (g/L)0.91 ± 0.250.92 ± 0.22−0.5760.565
Glu (mmol/L)5.10 (4.59–6.04)5.05 (4.62–5.92)− 0.4010.688
Bun (mmol/L)4.85 (3.91–5.74)4.90 (4.06–5.89)−0.9410.347
Cre (μmol/L)71 (62.8–80)71 (61.05–81)−0.0260.979
  1. The serum level of ApoB was examined by the independent samples T test, and the remaining serological biomarkers were examined by the Mann-Whitney test
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