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Table 2 Clinical parameters distributed in different genotypes

From: Analysis on the polymorphisms of site RS4977574, and RS1333045 in region 9p21 and the susceptibility of coronary heart disease in Chinese population

RS4977574

GG (n = 200)

AG (n = 419)

AA (n = 236)

P value

Age (years)

60 (51–68)

60 (52–69)

61 (52.25–68)

0.604

Gender (male/ female)

143/57

311/108

175/61

0.750

Smoking (yes/no)

89/111

189/230

106/130

0.990

Drinking (yes/no)

26/174

66/353

38/198

0.607

Hypertension (yes/no)

99/101

218/201

121/115

0.841

CKMB (U/L)

17 (13–22)

17 (13.40–21)

16 (12.10–21)

0.145

TC (mmol/L)

4.61 (3.93–5.48)

4.63 (3.92–5.40)

4.64 (3.75–5.61)

0.883

TG (mmol/L)

1.85 (1.26–2.41)

1.82 (1.23–2.55)

1.68 (1.13–2.43)

0.188

HDL (mmol/L)

1.32 (1.10–1.62)

1.37 (1.14–1.63)

1.41 (1.15–1.67)

0.208

LDL (mmol/L)

2.83 (2.26–3.45)

2.77 (2.15–3.40)

2.71 (2.14–3.53)

0.394

ApoA (g/L)

1.27 (1.13–1.42)

1.30 (1.16–1.46)

1.30 (1.16–1.46)

0.086

ApoB (g/L)

0.90 ± 0.21

0.93 ± 0.22

0.91 ± 0.24

0.305

Glu (mmol/L)

5.04 (4.55–5.80)

5.07 (4.63–6.00)

5.09 (4.59–6.07)

0.504

Bun (mmol/L)

4.87 (4.02–5.61)

4.87 (4.06–6.08)

4.94 (3.96–5.80)

0.381

Cre (μmol/L)

69 (61–81)

72 (62–82)

70 (62–79.75)

0.182

Gensini

20 (5–45.75)

18 (3–48)

10 (1.25–40)

0.017

HWE

   

0.596

RS1333045

TT (n = 211)

TC (n = 419)

CC (n = 225)

P value

Age (years)

61 (53–68)

60 (52–70)

60 (51.5–68)

0.697

Gender (male/ female)

159/52

304/115

166/59

0.751

Smoking (yes/no)

97/114

185/234

102/123

0.901

Drinking (yes/no)

38/173

63/356

29/196

0.327

Hypertension (yes/no)

106/105

218/201

114/111

0.896

CKMB (U/L)

16 (12.4–21)

17 (13–21)

17 (13–22)

0.446

TC (mmol/L)

4.60 (3.74–5.62)

4.65 (3.93–5.40)

4.62 (3.91–5.51)

0.933

TG (mmol/L)

1.71 (1.15–2.46)

1.74 (1.19–2.48)

1.90 (1.27–2.47)

0.168

HDL (mmol/L)

1.38 (1.13–1.67)

1.38 (1.14–1.63)

1.32 (1.11–1.62)

0.336

LDL (mmol/L)

2.64 (2.09–3.48)

2.75 (2.18–3.36)

2.94 (2.27–3.51)

0.087

ApoA (g/L)

1.29 (1.15–1.46)

1.30 (1.17–1.49)

1.27 (1.13–1.43)

0.129

ApoB (g/L)

0.91 ± 0.25

0.93 ± 0.22

0.90 ± 0.21

0.382

Glu (mmol/L)

5.10 (4.59–6.04)

5.05 (4.63–6.02)

5.07 (4.57–5.79)

0.493

Bun (mmol/L)

4.85 (3.91–5.74)

4.88 (4.07–6.14)

4.93 (4.04–5.78)

0.392

Cre (μmol/L)

71 (62.8–80)

62 (71–82)

69 (61–81)

0.463

Gensini

12 (2–40)

16 (3–45)

20 (4–48)

0.088

HWE

   

0.566

  1. HWE: P value for Hardy-Weinberg equilibrium test. Skewed data are presented as the median (interquartile range), normal data are presented as the mean ± standard deviation, and categorical data are presented as the absolute value. The serum level of ApoB was examined by one-way ANOVA, and the remaining baseline characteristics were examined by Kruskal-Wallis tests
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BMC Medical Genetics

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