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Table 2 Clinical parameters distributed in different genotypes

From: Analysis on the polymorphisms of site RS4977574, and RS1333045 in region 9p21 and the susceptibility of coronary heart disease in Chinese population

RS4977574GG (n = 200)AG (n = 419)AA (n = 236)P value
Age (years)60 (51–68)60 (52–69)61 (52.25–68)0.604
Gender (male/ female)143/57311/108175/610.750
Smoking (yes/no)89/111189/230106/1300.990
Drinking (yes/no)26/17466/35338/1980.607
Hypertension (yes/no)99/101218/201121/1150.841
CKMB (U/L)17 (13–22)17 (13.40–21)16 (12.10–21)0.145
TC (mmol/L)4.61 (3.93–5.48)4.63 (3.92–5.40)4.64 (3.75–5.61)0.883
TG (mmol/L)1.85 (1.26–2.41)1.82 (1.23–2.55)1.68 (1.13–2.43)0.188
HDL (mmol/L)1.32 (1.10–1.62)1.37 (1.14–1.63)1.41 (1.15–1.67)0.208
LDL (mmol/L)2.83 (2.26–3.45)2.77 (2.15–3.40)2.71 (2.14–3.53)0.394
ApoA (g/L)1.27 (1.13–1.42)1.30 (1.16–1.46)1.30 (1.16–1.46)0.086
ApoB (g/L)0.90 ± 0.210.93 ± 0.220.91 ± 0.240.305
Glu (mmol/L)5.04 (4.55–5.80)5.07 (4.63–6.00)5.09 (4.59–6.07)0.504
Bun (mmol/L)4.87 (4.02–5.61)4.87 (4.06–6.08)4.94 (3.96–5.80)0.381
Cre (μmol/L)69 (61–81)72 (62–82)70 (62–79.75)0.182
Gensini20 (5–45.75)18 (3–48)10 (1.25–40)0.017
HWE   0.596
RS1333045TT (n = 211)TC (n = 419)CC (n = 225)P value
Age (years)61 (53–68)60 (52–70)60 (51.5–68)0.697
Gender (male/ female)159/52304/115166/590.751
Smoking (yes/no)97/114185/234102/1230.901
Drinking (yes/no)38/17363/35629/1960.327
Hypertension (yes/no)106/105218/201114/1110.896
CKMB (U/L)16 (12.4–21)17 (13–21)17 (13–22)0.446
TC (mmol/L)4.60 (3.74–5.62)4.65 (3.93–5.40)4.62 (3.91–5.51)0.933
TG (mmol/L)1.71 (1.15–2.46)1.74 (1.19–2.48)1.90 (1.27–2.47)0.168
HDL (mmol/L)1.38 (1.13–1.67)1.38 (1.14–1.63)1.32 (1.11–1.62)0.336
LDL (mmol/L)2.64 (2.09–3.48)2.75 (2.18–3.36)2.94 (2.27–3.51)0.087
ApoA (g/L)1.29 (1.15–1.46)1.30 (1.17–1.49)1.27 (1.13–1.43)0.129
ApoB (g/L)0.91 ± 0.250.93 ± 0.220.90 ± 0.210.382
Glu (mmol/L)5.10 (4.59–6.04)5.05 (4.63–6.02)5.07 (4.57–5.79)0.493
Bun (mmol/L)4.85 (3.91–5.74)4.88 (4.07–6.14)4.93 (4.04–5.78)0.392
Cre (μmol/L)71 (62.8–80)62 (71–82)69 (61–81)0.463
Gensini12 (2–40)16 (3–45)20 (4–48)0.088
HWE   0.566
  1. HWE: P value for Hardy-Weinberg equilibrium test. Skewed data are presented as the median (interquartile range), normal data are presented as the mean ± standard deviation, and categorical data are presented as the absolute value. The serum level of ApoB was examined by one-way ANOVA, and the remaining baseline characteristics were examined by Kruskal-Wallis tests
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