Table 1 Demographics of the study population
Variables | CHDs (n = 598) | Controls (n = 257) | Statistical parameter | P value |
|---|---|---|---|---|
Age (years) | 61 (53–70) | 58 (49.5–66) | −3.839 | < 0.001 |
Gender (male/ female) | 465/133 | 164/93 | 17.978 | < 0.001 |
Smoking Status (yes/no) | 283/315 | 101/156 | 4.679 | 0.031 |
Drinking Status (yes/no) | 96/502 | 34/223 | 1.112 | 0.292 |
Hypertension (yes/no) | 324/274 | 114/143 | 6.941 | 0.008 |
CKMB (U/L) | 17 (13–23) | 16 (13–20) | −2.804 | 0.005 |
TC (mmol/L) | 4.65 (3.88–5.52) | 4.60 (3.91–5.38) | −0.837 | 0.403 |
TG (mmol/L) | 1.80 (1.25–2.48) | 1.71 (1.16–2.46) | − 1.139 | 0.255 |
HDL (mmol/L) | 1.33 (1.10–1.62) | 1.41 (1.18–1.68) | −2.426 | 0.015 |
LDL (mmol/L) | 2.79 (2.19–3.48) | 2.71 (2.17–3.38) | −1.325 | 0.185 |
ApoA (g/L) | 1.29 (1.14–1.45) | 1.30 (1.18–1.49) | −1.747 | 0.081 |
ApoB (g/L) | 0.92 ± 0.23 | 0.90 ± 0.21 | −1.234 | 0.218 |
Glu (mmol/L) | 5.19 (4.65–6.16) | 4.84 (4.53–5.34) | −5.447 | < 0.001 |
Bun (mmol/L) | 4.90 (4.05–5.88) | 4.87 (4.05–5.80) | −0.241 | 0.809 |
Cre (μmol/L) | 72 (62–81.25) | 69 (60–78) | −2.937 | 0.003 |
RS4977574 (GG/AG/AA) | 152/297/149 | 48/122/87 | 8.686 | 0.012 |
RS1333045 (TT/TC/CC) | 138/292/168 | 73/127/57 | 4.470 | 0.107 |