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Table 5 The association between uncoupling proteins and diabetic retinopathy in participants with and without controlled glucose

From: Analysis of association between common variants of uncoupling proteins genes and diabetic retinopathy in a Chinese population

Chr.a

rs ID

Position (hg19)

A1b

Well controlled glucose (172 cases vs 684 controls)

Uncontrolled glucose (356 cases vs 660 controls)

ORc [95% CId]

P

OR [95% CI]

P

4

rs6818140

141,487,955

G

0.857 [0.617–1.190]

0.357

1.164 [0.908–1.493]

0.231

4

rs7688743

141,488,795

A

0.935 [0.709–1.232]

0.634

1.309 [1.061–1.615]

0.012

4

rs10011540

141,489,996

G

1.129 [0.745–1.711]

0.567

1.432 [1.045–1.963]

0.033

4

rs3811787

141,490,419

T

0.959 [0.760–1.210]

0.724

0.811 [0.677–0.971]

0.022

4

rs3811790

141,491,576

A

0.978 [0.766–1.250]

0.862

0.962 [0.795–1.163]

0.687

4

rs3811791

141,491,773

C

1.121 [0.855–1.470]

0.408

0.921 [0.742–1.143]

0.454

4

rs1472268

141,492,943

A

1.098 [0.870–1.387]

0.432

0.927 [0.774–1.112]

0.416

4

rs1800592

141,493,961

T

1.105 [0.874–1.396]

0.404

0.927 [0.774–1.112]

0.416

11

rs659366

73,694,754

T

1.065 [0.829–1.368]

0.624

0.936 [0.773–1.134]

0.500

11

rs591758

73,698,060

C

1.092 [0.851–1.400]

0.491

0.908 [0.750–1.099]

0.320

11

rs1685356

73,712,859

T

0.927 [0.731–1.176]

0.534

1.169 [0.972–1.406]

0.096

11

rs3741135

73,713,960

A

1.139 [0.888–1.461]

0.305

0.935 [0.772–1.131]

0.488

11

rs2734827

73,716,277

A

0.532 [0.286–0.989]

0.017

1.153 [0.753–1.765]

0.514

  1. a Chr. chromosome, b A1 effect allele, c OR odds ratio, d CI confidence Interval