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Table 1 Characteristics of studies included in meta-analysis of overall asthma

From: Interleukin-4 gene polymorphism (C33T) and the risk of the asthma: a meta-analysis based on 24 publications

Study author Year Country continent Ethnicity Sex
cases/controls
Total cases/control Age case/control Genotyping method Quality score
Suzuki et al. 2000 Japan Asian Caucasian M = 50/60
F = 100/150
120 / 120 Adult PCR-RFLP 6
Beghe et al. 2003 UK European Caucasian M = 88/99
F = 93/89
187 / 182 Adult PCR-RFLP 7
Basehore et al. (i) 2004 USA American (USA white) Caucasian M = 93/140
F = 98/147
233 / 245 Adult PCR 7
Basehore et al.(ii) 2004 USA American American- African M = 77/91
F = 121/148
168 / 269 Adult PCR 6
Basehore et al.(iii) 2004 USA American (USA Hispanic) Caucasian (Hispanic) M = 54/62
F = 41/89
116 / 130 Adult PCR 6
Park et al. 2004 Korea Asian Caucasian M = 248/302
F = 85/86
532 / 170 Mixed SnaP shot 8
Donfack et al. (i) 2005 USA American Caucasian M = NR
F=NR
126 / 205 Mixed LAS 6
Donfack et al.(ii) 2005 USA American American- African M = NR
F=NR
205 / 183 Mixed LAS 6
Garcia et al. 2005 Spain European Caucasian M = NR
F=NR
133 / 79 Mixed TaqMan 6
Battle et al. 2007 USA American American- African M = 105/156
F = 67/109
261 / 176 Mixed PCR-RFLP 6
Amirzargar et al. 2009 Iran Asian Caucasian M = NR
F=NR
59 / 139 Mixed PCR-SSP 5
Jiang et al. 2009 China Asian Caucasian M = NR
F = NR
24 / 24 Adult PCR-RFLP 5
Daley et al. 2009 Australia Australian Caucasian M = NR
F = NR
643 / 751 Mixed Illumina Bead array system 8
Haller et al. 2009 USA American American- African M = NR
F=NR
72 / 70 Adult PCR-RFLP 6
Wang et al. 2009 Taiwan Asian Caucasian M = 299/147
F = 245/265
446 / 510 Children TaqMan 7
Berce et al. 2010 Slovenia European Caucasian M = NR
F=NR
106 / 89 Children PCR-RFLP 6
Undarmaa et al. (i) 2010 Japan Asian Caucasian M = NR
F=NR
324 / 336 Children TaqMan-ASA 7
Undarmaa et al.(ii) 2010 Japan Asian Caucasian M = NR
F=NR
367 / 676 Adult TaqMan-ASA 8
Wu et al. 2010 China Asian Caucasian M = 138/114
F = 118/109
252 / 227 Children PCR-RFLP 7
Michel et al. 2010 Germany European Caucasian M = NR
F=NR
703 / 658 Children Illumina Sentrix Bead chip 8
Huang et al. 2011 China Asian Caucasian M = 51/49
F = 70/52
100 / 122 Children PCR-RFLP 6
Yang et al. 2011 China Asian Caucasian M = 101/101
F = 155/50
202 / 205 Adult MALDI-TOF 6
Chen et al. 2011 China Asian Caucasian M = NR
F=NR
202 / 191 Children MALDI-TOF 7
Micheal et al. 2013 Pakistan Asian Caucasian M = NR
F=NR
108 / 120 Mixed PCR-RFLP 6
Miyake et al. 2013 Japan Asian Caucasian M = 0/89
F = 0/1281
89 / 1281 Adult TaqMan 6
Davoodi et al. 2013 India Asian Caucasian M = 45/55
F = 21/29
100 / 50 Adult Mass Array 5
Wang et al. 2015 China Asian Caucasian M = NR
F=NR
392 / 849 Children Mass Array 8
Li et al. 2016 China Asian Caucasian M = 134/183
F = 151/200
317 / 351 Children PCR-RFLP 7
  1. NR not reported, M male, F female