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Table 1 Clinical, pathological, cytogenetic, and molecular findingsa

From: KANK1-NTRK3 fusions define a subset of BRAF mutation negative renal metanephric adenomas

Case no. Age range years Gender Tumor Size (cm) Laterality Karyotype BRAF Status t(9;15)(p24;q24) FISH
1. 21–30 F 2 Right 46,XX,t(9;15)(p24;q24) Wild type Fusion Present
2. 21–30 F 3 Left 46,XX,t(6;22)(q26;q11.2) Wild type Normal
3. 41–50 M 12 NA 46,XY V600E Mutation Normal
4. 51–60 F 1.4 Left 46,XX V600E Mutation Normal
5. 51–60 M 3 Right 46,XY V600E Mutation Normal
6. 31–40 F 6.7 Left NA V600E Mutation Normal
7. 61–70 F NA Right NA Uninformative Uninformative
8. 51–60 M NA NA NA V600E Mutation Uninformative
9. 51–60 F 0.5 Right NA Uninformative Uninformative
10. 61–70 F 5.1 Right NA V600E Mutation Normal
11. 31–40 F 3.4 Left NA V600E Mutation Normal
12. 1–10 M 1.7 Right 46,XY,t(9;15)(p24;q24),inv.(12)(q13q15) Wild type Fusion Present
13. 1–10 M 1.5 Right NA V600E Mutation Normal
14. 31–40 M 4.3 NA NA V600E Mutation Normal
15. 11–20 M 7 Right NA Wild type Normal
16. NA NA NA NA NA Wild type Normal
17. 51–60 F NA Left NA Wild type Normal
18. 51–60 F 5 NA NA Uninformative Uninformative
19. 71–80 M 1.8 Right NA Wild type Normal
20 21–30 F 2 NA NA Wild type Uninformative
21. 61–70 F 4 NA NA Wild type Uninformative
22. 71–80 F 2.5 NA NA V600E Mutation Normal
23. 51–60 F 5 NA NA Uninformative Uninformative
24. 51–60 F 3 NA NA V600E Mutation Normal
25. 11–20 F 3 Right NA V600E Mutation Normal
26. 41–50 F 1.5 NA NA V600E Mutation Uninformative
27. 61–70 M 8 NA NA V600E Mutation Normal
28. 61–70 M 3 NA NA V600E Mutation Normal
  1. aAbbreviations: NA indicates not available, FISH Fluorescent in situ hybridization