Table 4 Association between DNMT3A rs13428812 and CpG methylation of each genes
From: Effect of DNMT3A polymorphisms on CpG island hypermethylation in gastric mucosa
genotype | p14ARF-UM (343) | p14ARF-M (167) | adjusted OR* (95%CI); p value | |
AA | 202 | 111 | reference | reference |
AG | 119 | 47 | 0.77 (0.52–1.14); 0.19 | |
GG | 22 | 9 | 0.93 (0.41–2.10); 0.87 | |
genotype | p16INK4a-UM (376) | p16INK4a-M (134) | adjusted OR* (95%CI); p value | |
AA | 216 | 97 | reference | reference |
AG | 138 | 28 | 0.55 (0.35–0.85); 0.0078 | |
GG | 22 | 9 | 1.44 (0.62–3.37); 0.40 | |
genotype | DAPK-UM (258) | DAPK-M (252) | adjusted OR* (95%CI); p value | |
AA | 144 | 169 | reference | reference |
AG | 93 | 73 | 0.66 (0.46–0.96); 0.030 | |
GG | 21 | 10 | 0.53 (0.240–1.17); 0.12 | |
genotype | CDH1-UM (318) | CDH1-M (192) | adjusted OR* (95%CI); p value | |
AA | 168 | 145 | reference | reference |
AG | 129 | 37 | 0.37 (0.25–0.56); < 0.0001 | |
GG | 21 | 10 | 0.90 (0.40–2.00); 0.79 | |