Investigation of INDEL variants in apoptosis: the relevance to gastric cancer

BMC Medical Genetics

Table 1 Technical characterization of the markers included in the panel

Gene	ID	Region	Alleles	MAF	*Primers*	*Amplicon*
BCL2	rs11269260	Intron	TCTATCACCGATCATT/−	0.37	F5’GCTTCCAGTTCCATCCATGT3’ R5’CTCAGCGTGGTAGTGTTGGA3’	189–205
CASP3	rs4647655	Intron	−/AAATCCTGAA	0.28	F5’AGGAGTATCCCCTCGTGGAC3’ R5’CAAGAGTCAGGCAAAAACAGG3’	379–389
CASP8	rs3834129	Promoter	AGTAAG/−	0.39	F5’CTCTTCAATGCTTCCTTGAGGT3’ R5’CTGCATGCCAGGAGCTAAGTAT3’	249–255
CASP8	rs59308963	Intron	ATTCTGTC/−	0.26	F5’TTTTTGTCCTCCAAGCTTCC3’ R5’GAACAAGAGAGAGGGCAGGA3’	261–269
CASP9	rs4645982	Intron	−/TCCCCGCACTGACCTCACG	0.42	F5’GGTGACCCCAGAATTGACCCT3’ R5’GCCCTCAGGACGCACCTCTG3’	336–353
CASP9	rs61079693	Intron	AAAA/−	0.32	F5’CATGCACAGCTATCCAGGAG3’ R5’TTGTTCCTGTCCGATAGATGC3’	458–462
FADD	rs4197	3′ UTR	−/TGT	0.47	F5’TGCCCCTACTTAGCAGTCTCA3’ R5’GAGAGGTGGAGAACTGGGATT3’	278–281
FAS	rs10562972	Intron	TTC/−	0.12	F5’GCATCAGGACGCTGAACATA3’ R5’AATGCAACTTGCTCCAGAGG3’	368–371
TP53	rs17880560	3′-Flanking	−/GCCGTG	0.21	F5’CTGTGTGTCTGAGGGGTGAA3’ R5’ATCCTGCCACTTTCTGATGG3’	400–406

ISSN: 1471-2350