Table 2 Comparing the genotypes and alleles of LEPR c.668 A > G (Q223R) and LEPR c.1968G>C (K656N) between women with preeclampsia and the controls
Genotypes | Preeclampsia (122) | Controls (122) | Crude OR (95% CI) | P-value | aOR (95% CI) | P-value | ||
|---|---|---|---|---|---|---|---|---|
N | % | N | % | Â | Â | |||
LEPR c.668 A > G | ||||||||
 AA | 46 | 37.7 | 100 | 81.96 | Reference |  | Reference |  |
 AG | 46 | 37.7 | 19 | 15.57 | 4.41 (1.32–16.66) | 0.016 | 3. 48 (1.15–10.54) | 0.027 |
 GG | 30 | 24.6 | 3 | 2.5 | 16.65 (1.93–143.50) | < 0.001 | 14.19 (1.77–113.76) | 0.012 |
LEPR c.1968G>C | ||||||||
 GG | 111 | 91.0 | 118 | 96.7 | Reference |  | Reference |  |
 GC | 11 | 9.0 | 4 | 3.3 | 1.32 (0.81–2.13) | 0.258 | 3.08 (0.35–26.58) | 0.350 |
 CC | 0 | 0 | 0 | 0 | – | – | – | – |