Table 2 Meta-analysis of the association of PNPLA3 rs738409 G/C gene polymorphism and childhood NAFLD susceptibility
Genetic model | Relevance test | Heterogeneity test | Publication | |||||
|---|---|---|---|---|---|---|---|---|
OR(95% CI) | Z | Pvalue | I2 | Q | Phel | Pegger | t | |
dominant gene model | 3.157 (1.446–6.892) | 2.89 | 0.004 | 90.9 | 43.75 | 0.000 | 0.060 | 2.95 |
Allelic model | 3.343 (1.524–7.334) | 3.01 | 0.003 | 95.7 | 93.77 | 0.000 | 0.081 | 2.59 |
recessive model | 5.692 (1.941–16.689) | 3.17 | 0.002 | 90.7 | 42.91 | 0.000 | 0.076 | 2.67 |
super-dominant model | 2.756 (1.729–4.392) | 4.26 | 0.000 | 80.9 | 20.93 | 0.000 | 0.038 | −3.56 |