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Table 1 The main characteristics of the studies included in the meta-analysis

From: The genome-wide supported CACNA1C gene polymorphisms and the risk of schizophrenia: an updated meta-analysis

Author

Year

Country

Ancestor

Source of control group

Mean age of control group

Gender index (case)

Gender index (control)

Case/Control

Rs1006737

 Fatima [11]

2017

Pakistani

Caucasian

Population based

44

0.33

0.71

508/300

 Lubeiro [20]

2018

Spain

Caucasian

Population based

29.52

0.72

0.98

50/101

 Mallas [21]

2016

Mixed

Mixed

Population based

35.79

0.26

0.85

63/124

 Porcelli [22]

2015

Korean

Asian

Hospital based

45.36

0.73

1.22

176/326

 Ivorra [8]

2014

Spain

Caucasian

Mixed

43.61

0.79

0.75

3063/2847

 He [15]

2013

China

Asian

Population based

30.6

0.53

0.86

1235/1235

 Guan [23]

2013

China

Asian

Population based

34.2

0.87

0.83

1430/1570

 Galaktionova [24]

2013

Russia

Caucasian

Population based

36

2.24

0.90

188/192

 Zheng [13]

2013

China

Asian

Population based

32.4

1.05

1.04

5893/6319

 Hori [18]

2012

Japan

Asian

Population based

46

0.82

1.93

552/1132

 Zhang [25]

2011

China

Asian

Population based

22.3

0.49

0.60

318/401

 Nyegaard [26]

2010

Denmark

Caucasian

Population based

976/1489

 Bigos [27]

2010

 

Caucasian

Population based

33.09

0.230

1.16

282/440

 Green [28]

2009

UK

Caucasian

Population based

0.47

1.04

479/2936

Rs2007044

 Bustillo [29]

2017

United States

Caucasian

Population based

36

0.26

0.37

53/129

 Zhang [30]

2018

China

Asian

Hospital based

27.14

0.15

0.28

53/129

Rs4765905

 Sudesh [31]

2018

India

Indian

Population based

38.73

1.01

0.483

1005/1069

  1. Notes: Gender index = female/male; Guan’s study included the main characteristics of both rs1006737 and rs4765905; Zheng’s study included the main characteristics of both rs1006737 and rs2007044