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Table 1 The main characteristics of the studies included in the meta-analysis

From: The genome-wide supported CACNA1C gene polymorphisms and the risk of schizophrenia: an updated meta-analysis

Author Year Country Ancestor Source of control group Mean age of control group Gender index (case) Gender index (control) Case/Control
Rs1006737
 Fatima [11] 2017 Pakistani Caucasian Population based 44 0.33 0.71 508/300
 Lubeiro [20] 2018 Spain Caucasian Population based 29.52 0.72 0.98 50/101
 Mallas [21] 2016 Mixed Mixed Population based 35.79 0.26 0.85 63/124
 Porcelli [22] 2015 Korean Asian Hospital based 45.36 0.73 1.22 176/326
 Ivorra [8] 2014 Spain Caucasian Mixed 43.61 0.79 0.75 3063/2847
 He [15] 2013 China Asian Population based 30.6 0.53 0.86 1235/1235
 Guan [23] 2013 China Asian Population based 34.2 0.87 0.83 1430/1570
 Galaktionova [24] 2013 Russia Caucasian Population based 36 2.24 0.90 188/192
 Zheng [13] 2013 China Asian Population based 32.4 1.05 1.04 5893/6319
 Hori [18] 2012 Japan Asian Population based 46 0.82 1.93 552/1132
 Zhang [25] 2011 China Asian Population based 22.3 0.49 0.60 318/401
 Nyegaard [26] 2010 Denmark Caucasian Population based 976/1489
 Bigos [27] 2010   Caucasian Population based 33.09 0.230 1.16 282/440
 Green [28] 2009 UK Caucasian Population based 0.47 1.04 479/2936
Rs2007044
 Bustillo [29] 2017 United States Caucasian Population based 36 0.26 0.37 53/129
 Zhang [30] 2018 China Asian Hospital based 27.14 0.15 0.28 53/129
Rs4765905
 Sudesh [31] 2018 India Indian Population based 38.73 1.01 0.483 1005/1069
  1. Notes: Gender index = female/male; Guan’s study included the main characteristics of both rs1006737 and rs4765905; Zheng’s study included the main characteristics of both rs1006737 and rs2007044