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Table 6 Regression analysis to determine the effect age, sex and polymorphisms on glaucoma risk

From: Association analysis of polymorphisms rs12997 in ACVR1 and rs1043784 in BMP6 genes involved in bone morphogenic protein signaling pathway in primary angle-closure and pseudoexfoliation glaucoma patients of Saudi origin

Group
Variables
B SE Wald Odds ratio (95% confidence interval) p
PACG
 Age 0.016 0.016 0.995 1.02 (0.98–1.04) 0.319
 Sex −0. 467 0.255 3.371 0. 62 (0.38–1.03) 0. 066
 Rs12997    7.904   0.019
 A/G −0. 262 0. 281 0. 870 0.77 (0.44–1.33) 0.351
 G/G 0.748 0.354 4.457 2.11 (1.05–4.23) 0.035
 Rs1043784    0.675   0.714
 T/C 0.185 0.297 0.389 1.20 (0.67–2.15) 0.533
 C/C −0.329 0.709 0.216 0.72 (0.18–2.88) 0.642
 Constant −1.498 0.961 2.43 0.223 0.119
PXG
 Age 0.075 0.017 20.488 1.08 (1.04–1.11) 0.000
 Sex −0.299 0.278 1.159 1.34 (0.78–2.32) 0.282
 Rs12997    6.227   0.044
 A/G 0.188 0.295 0.404 1.20 (0.67–2.15) 0.525
 G/G 1.033 0.418 6.107 2.81 (1.23–6.37) 0.013
 Rs1043784    2.932   0.231
 T/C 0.455 0.303 2.26 1.57 (0.87–2.85) 0.133
 C/C −0.559 0.854 0.427 0.57 (0.10–3.05) 0.513
 Constant −6.028 1.095 30.318 0.002 0.000
  1. Abbreviations: PACG primary angle-closure glaucoma, PXG pseudoexfoliation glaucoma
  2. Significant p-value in bold