Group | Genetic Model | Genotype | Control n (%) | PXG n (%) | OR (95% CI) | p | AIC | BIC | p§ |
---|---|---|---|---|---|---|---|---|---|
Overall | Co-dominant | A/A | 110 (44.4) | 34 (35.8) | 1.00 | 0.150 | 407.0 | 418.6 | 0.52 |
A/G | 111 (44.8) | 44 (46.3) | 1.28 (0.76–2.16) | ||||||
G/G | 27 (10.9) | 17 (17.9) | 2.04 (0.99–4.18)† | ||||||
Dominant | A/A | 110 (44.4) | 34 (35.8) | 1.00 | 0.150 | 406.7 | 414.4 | 0.34 | |
A/G-G/G | 138 (55.6) | 61 (64.2) | 1.43 (0.88–2.33) | ||||||
Recessive | A/A-A/G | 221 (89.1) | 78 (82.1) | 1.00 | 0.091 | 405.9 | 413.6 | 0.37 | |
G/G | 27 (10.9) | 17 (17.9) | 1.78 (0.92–3.45) | ||||||
Over-dominant | A/A-G/G | 137 (55.2) | 51 (53.7) | 1.00 | 0.800 | 408.7 | 416.4 | 0.7 | |
A/G | 111 (44.8) | 44 (46.3) | 1.06 (0.66–1.71) | ||||||
Log-additive | – | – | – | 1.39 (0.99–1.97) | 0.059* | 405.2 | 412.9 | 0.25 | |
Men | Co-dominant | A/A | 55 (41.0) | 23 (37.7) | 1.00 | 0.460 | 246.8 | 256.6 | 0.82 |
A/G | 62 (46.3) | 26 (42.6) | 1.00 (0.51–1.96) | ||||||
G/G | 17 (12.7) | 12 (19.7) | 1.69 (0.70–4.09) | ||||||
Dominant | A/A | 55 (41.0) | 23 (37.7) | 1.00 | 0.660 | 246.1 | 252.7 | 0.83 | |
A/G-G/G | 79 (59.0) | 38 (62.3) | 1.15 (0.62–2.14) | ||||||
Recessive | A/A-A/G | 117 (87.3) | 49 (80.3) | 1.00 | 0.210 | 244.8 | 251.3 | 0.53 | |
G/G | 17 (12.7) | 12 (19.7) | 1.69 (0.75–3.79) | ||||||
Over-dominant | A/A-G/G | 72 (53.7) | 35 (57.4) | 1.00 | 0.630 | 246.1 | 252.6 | 0.85 | |
A/G | 62 (46.3) | 26 (42.6) | 0.86 (0.47–1.59) | ||||||
Log-additive | – | – | – | 1.24 (0.80–1.90) | 0.340 | 245.4 | 252 | 0.64 | |
Women | Co-dominant | A/A | 55 (48.2) | 11 (32.4) | 1.00 | 0.230 | 162.5 | 171.5 | 0.45 |
A/G | 49 (43.0) | 18 (52.9) | 1.84 (0.79–4.27) | ||||||
G/G | 10 (8.8) | 5 (14.7) | 2.50 (0.71–8.76) | ||||||
Dominant | A/A | 55 (48.2) | 11 (32.4) | 1.00 | 0.098 | 160.8 | 166.8 | 0.22 | |
A/G-G/G | 59 (51.8) | 23 (67.7) | 1.95 (0.87–4.37) | ||||||
Recessive | A/A-A/G | 104 (91.2) | 29 (85.3) | 1.00 | 0.330 | 162.6 | 168.6 | 0.54 | |
G/G | 10 (8.8) | 5 (14.7) | 1.79 (0.57–5.66) | ||||||
Over-dominant | A/A-G/G | 65 (57.0) | 16 (47.1) | 1.00 | 0.310 | 162.5 | 168.5 | 0.38 | |
A/G | 49 (43.0) | 18 (52.9) | 1.49 (0.69–3.22) | ||||||
Log-additive | – | – | – | 1.64 (0.92–2.93) | 0.091 | 160.7 | 166.7 | 0.22 |