Association analysis of polymorphisms rs12997 in ACVR1 and rs1043784 in BMP6 genes involved in bone morphogenic protein signaling pathway in primary angle-closure and pseudoexfoliation glaucoma patients of Saudi origin

Table 1 Minor allele frequency of rs12997[G] polymorphism in cases and controls

Type Group	Cases MAF	Controls MAF	Odds ratio (95% confidence interval)	p
PACG
Total	0.41	0.33	1.40 (0.99–1.96)	0.050
Men	0.35	0.36	0.97 (0.58–1.61)	0.920
Women	0.46	0.30	1.93 (1.21–3.07)	0.005
PXG
Total	0.41	0.33	1.39 (0.99–1.97)	0.056
Men	0.41	0.36	1.24 (0.89–1.93)	0.329
Women	0.41	0.30	1.61 (0.92–2.82)	0.092

Abbreviation: PACG primary angle-closure glaucoma, PXG pseudoexfoliation glaucoma, MAF minor allele frequency
Significant and trend p-value in bold

ISSN: 1471-2350