Fig. 3

a: Structural superposition of wild type (blue) and the p.D450Nfs*95 mutated IDS protein (green). The deleted part of the mutate protein (red) correspond the C-terminal of the heavy chain (5 amino acids) and the all part of the light chain (14KDa). PyMOL; pdb = 5FQL. b Structural superposition of wild type (blue) and the p.Q204* mutated IDS protein (light blue). The deleted part of the mutate protein (red) correspond the active site and the C-terminal of the heavy chain PyMOL; pdb = 5FQL