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Fig. 3 | BMC Medical Genetics

Fig. 3

From: Niemann-Pick disease type-B: a unique case report with compound heterozygosity and complicated lipid management

Fig. 3

a. Liver biopsy demonstrates enlarged hepatocytes with a finely vacuolated cytoplasm and generalised foamy Kupffer cells filling the sinusoids (H-E staining x 200). b. Trichrome-stained sections show minimal perisinusoidal fibrosis (x 200). c. Higher magnification shows cytoplasmic vacuolization in hepatocytes (H), as well as in Kupffer cells (K) (H-E staining x 1000). d. Positive strong reactivity for CD68 highlights sinusoidal cells

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BMC Medical Genetics

ISSN: 1471-2350

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