Association analysis between the tag single nucleotide polymorphisms of DENND1A and the risk of polycystic ovary syndrome in Chinese Han women

Table 3 Genotypes and alleles of rs2479106, rs2768819, rs2670139, rs2536951 and rs2479102 in PCOS cases and controls

rs2479106	Genotypes, n (%)			p-value^a	Alleles, n (%)		p-value^b
rs2479106	AG	AA	GG	p-value^a	A	G	p-value^b
Control	78(0.347)	140(0.622)	7(0.031)	0.277	358(0.796)	92(0.204)	0.37
PCOS	115(0.332)	210(0.607)	21(0.061)	0.277	535(0.773)	157(0.227)	0.37
rs2768819	Genotypes, n (%)			p-value^a	Alleles, n (%)		p-value^b
rs2768819	AG	AA	GG	p-value^a	A	G	p-value^b
Control	31(0.365)	52(0.612)	2(0.024)	0.842	135(0.794)	35(0.206)	0.985
PCOS	89(0.344)	161(0.622)	9(0.035)	0.842	411(0.793)	107(0.207)	0.985
rs2670139	Genotypes, n (%)			p-value^a	Alleles, n (%)		p-value^b
rs2670139	CT	CC	TT	p-value^a	C	T	p-value^b
Control	65(0.284)	25(0.109)	139(0.607)	0.465	115(0.251)	343(0.749)	0.23
PCOS	89(0.282)	25(0.079)	202(0.639)	0.465	139(0.220)	493(0.780)	0.23
rs2536951	Genotypes, n (%)			p-value^a	Alleles, n (%)		p-value^b
rs2536951	AG	AA	GG	p-value^a	A	G	p-value^b
Control	67(0.307)	116(0.532)	35(0.161)	< 0.001	299(0.686)	137(0.314)	< 0.001
PCOS	82(0.288)	188(0.660)	15(0.053)	< 0.001	458(0.804)	112(0.196)	< 0.001
rs2479102	Genotypes, n (%)			p-value^a	Alleles, n (%)		p-value^b
rs2479102	CT	CC	TT	p-value^a	C	T	p-value^b
Control	61(0.269)	37(0.163)	129(0.568)	< 0.001	135(0.297)	319(0.703)	< 0.001
PCOS	86(0.304)	12(0.042)	185(0.654)	< 0.001	110(0.194)	456(0.806)	< 0.001

ISSN: 1471-2350