Skip to main content
Fig. 5 | BMC Medical Genetics

Fig. 5

From: POLE mutations improve the prognosis of endometrial cancer via regulating cellular metabolism through AMF/AMFR signal transduction

Fig. 5

POLE mutations regulate cellular metabolism through enhancing AMF/PGI and AMFR/gp78 expression. a The expression of AMF/PGI in endometrial cancer patients and normal samples, Normal = 35, Cancer = 551. The Y axis represents the expression of the gene (log2FPKM). b The expression of AMF/PGI in mutant and wild type POLE endometrial cancer samples, Mutant = 80, wild type = 446. The Y axis represents the expression of the gene (FPKM). c The expression of AMFR/gp78 in mutant and wild type POLE endometrial cancer samples, Mutant = 80, wild type = 446. The Y axis represents the expression of the gene (FPKM). d Kaplan–Meier curve and log-rank test for endometrial cancer patients based on the comprehensive expression of POLE and AMFR/gp78 classification

Back to article page

BMC Medical Genetics

ISSN: 1471-2350

Contact us