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Fig. 4 | BMC Medical Genetics

Fig. 4

From: Copy number variation is highly correlated with differential gene expression: a pan-cancer study

Fig. 4

Identification of AUGs and DDGs across 31 various cancer types in TCGA. a. Representative AUGs (see Methods) were identified by the concordant rate of copy number amplification and expression level upregulation against copy number deletion and expression level downregulation and spearman correlation coefficient (the right barchart). The heatmap (left) shows the corresponding variant rate in each cancer type for each AUG. b. Representative DDGs were identified by the concordant rate of copy number deletion and expression level downregulation against copy number amplification and expression level upregulation and spearman correlation coefficient (the right barchart). The heatmap (left) shows the corresponding variant rate in each cancer type for each DDG. A&U: copy number amplification and expression level upregulation. D&D: copy number deletion and expression level downregulation

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