Table 2 Influence of UGT1A1 (TA) n genotype on laboratory parameters of patients

Total Bilirubin (mg/dl)

2.8 (1.2–8.1)

1.8 (0.8–4.6)

1.4 (0.4–3.8)

1.4 (0.5–2.8)

< 0.0001** ¹

Unconjugated Bilirubin (mg/dl)

1.8 (0.6–6.3)

0.8 (0.1–3.3)

0.6 (0.1–2.3)

0.5 (0.3–1.6)

< 0.0001** ¹

LDH (IU/L)

987 (296–1860)

798 (215–1489)

789 (340–1417)

287 (197–800)

0.0002** ²

AST (IU/L)

46 (18–89)

37 (8–89)

42 (7–89)

39 (18–89)

0.4837**

ALT (IU/L)

25 (4–65)

19 (7–77)

20 (7–44)

12 (4–34)

0.216**

Hb conc (g/dl)

7.3 (6.3–10)

7.5 (6.3–9.7)

7.2 (6.2–10)

7.9 (7–8.8)

0.608**

MCV (fl)

80.6 (66.9–104.1)

82.3 (60.3–10.2)

77.3 (63.9–96.3)

81 (55.9–115)

0.642**

RBC (×  10¹²/L)

2.7 (1.9–4.1)

2.7 (1.8–4.1)

2.9 (1.8–4.8)

2.8 (2.2–3.9)

0.258**

WBC (×  10⁹/L)

13 (8.5–26)

13.4 (6.1–29.3)

13.3 (7–25)

12.2 (7.6–23.1)

0.889**

Platelet (×  10⁹/L)

367 (118–771)

349 (159–601)

361 (108–669)

391 (135–832)

0.955**

HbF (%)

9.7 (1.3–20.6)

8.2 (1.7–24.4)

10.7 (2.5–32)

9.4 (0.9–28.5)

0.86**

HbS (%)

80 (71–91.5)

82 (44–91.5)

80 (44–88.3)

80 (65–89)

0.90**

HbA2 (%)

1.6 (0.5–3.5)

1.7 (0.2–3.8)

1.5 (0.2–4.0)

1.1 (0.3–3.1)

0.3147**