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Table 1 Clinical features of the affected individuals

From: A novel missense in GLI3 possibly affecting one of the zinc finger domains may lead to postaxial synpolydactyly: case report

Affected individualSexAgeSymptomsMutation
Great-grandmother (individual I:2)FemaleDeceasedBoth hands were classified as post-axial polydactyly type B
Granduncle (individual II:2)Male56 yearsBoth hands were classified as post-axial polydactyly type B
Grandfather (individual II:6)Male54 yearsBoth hands were classified as post-axial polydactyly type Bc.[1622C > T];p.[(Thr541Met)]
Father (individual III:2)Male34 yearsLeft hand was classified as post-axial polydactyly type Bc.[1622C > T];p.[(Thr541Met)]
Patient (individual IV:1)Male2 yearsRight hand was classified as post-axial polydactyly, left hand had cutaneous webbing between the 3rd and 4th fingers, left foot had a well-formed digit on the fibular aspect.c.[1622C > T];p.[(Thr541Met)]