Table 2 Associations between the polymorphisms in DGCR8 gene and preeclampsia subtypes
From: Genetic polymorphism in DGCR8 is associated with late onset of preeclampsia
Genotype | Controls | EOPE | LOPE | ||||||
|---|---|---|---|---|---|---|---|---|---|
N (%) | N (%) | OR (95%CI) | p | p a | N (%) | OR (95%CI) | p | p a | |
rs1558496 | |||||||||
TT | 288(87.27) | 54(81.82) | 1.00 | 185(89.81) | 1.00 | ||||
TC | 40(12.12) | 10(15.15) | 1.33(0.63, 2.83) | 0.453 | 0.755 | 20(9.71) | 0.78(0.44, 1.37) | 0.387 | 0.484 |
CC | 2(0.61) | 2(3.03) | 5.33(0.74, 38.69) | 0.097 | 0.485 | 1(0.49) | 0.78(0.07, 8.64) | 0.838 | 0.838 |
rs1640299 | |||||||||
TT | 195(59.09) | 38(57.58) | 1.00 | 85(41.26) | 1.00 | ||||
TG | 120(36.36) | 23(34.85) | 0.98(0.56, 1.73) | 0.954 | 0.979 | 104(50.49) | 1.98(1.38, 2.87) | 2.32e-4 | 5.80e-4 |
GG | 15(4.55) | 5(7.58) | 1.71(0.59, 4.99) | 0.325 | 0.530 | 17(8.25) | 2.60(1.24, 5.45) | 0.011 | 0.055 |
rs720012 | |||||||||
GG | 64(19.39) | 14(21.21) | 1.00 | 45(21.84) | 1.00 | ||||
GA | 154(46.67) | 34(51.52) | 1.00(0.51, 2.00) | 0.979 | 0.979 | 115(55.83) | 1.06(0.68, 1.67) | 0.794 | 0.794 |
AA | 112(33.94) | 18(27.27) | 0.74(0.34, 1.58) | 0.428 | 0.530 | 46(22.33) | 0.58(0.35, 0.98) | 0.040 | 0.067 |
rs720014 | |||||||||
TT | 231(70.00) | 50(75.76) | 1.00 | 99(48.06) | 1.00 | ||||
TC | 91(27.58) | 13(19.70) | 0.66(0.34, 1.27) | 0.215 | 0.538 | 97(47.09) | 2.49(1.72, 3.60) | 1.40e-7 | 7.00e-07 |
CC | 8(2.42) | 3(4.55) | 1.73(0.44, 6.76) | 0.429 | 0.530 | 10(4.85) | 2.92(1.12, 7.61) | 0.0287 | 0.067 |
rs9606241 | |||||||||
AA | 240(72.73) | 41(62.12) | 1.00 | 139(67.48) | 1.00 | ||||
AG | 83(25.15) | 23(34.85) | 1.62(0.92, 2.86) | 0.095 | 0.475 | 60(29.13) | 1.25(0.84, 1.85) | 0.268 | 0.447 |
GG | 7(2.12) | 2(3.03) | 1.67(0.34, 8.33) | 0.530 | 0.530 | 7(3.40) | 1.27(0.59, 5.03) | 0.316 | 0.395 |