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Table 2 Associations between the polymorphisms in DGCR8 gene and preeclampsia subtypes

From: Genetic polymorphism in DGCR8 is associated with late onset of preeclampsia

Genotype Controls EOPE LOPE
N (%) N (%) OR (95%CI) p p a N (%) OR (95%CI) p p a
rs1558496
 TT 288(87.27) 54(81.82) 1.00    185(89.81) 1.00   
 TC 40(12.12) 10(15.15) 1.33(0.63, 2.83) 0.453 0.755 20(9.71) 0.78(0.44, 1.37) 0.387 0.484
 CC 2(0.61) 2(3.03) 5.33(0.74, 38.69) 0.097 0.485 1(0.49) 0.78(0.07, 8.64) 0.838 0.838
rs1640299
 TT 195(59.09) 38(57.58) 1.00    85(41.26) 1.00   
 TG 120(36.36) 23(34.85) 0.98(0.56, 1.73) 0.954 0.979 104(50.49) 1.98(1.38, 2.87) 2.32e-4 5.80e-4
 GG 15(4.55) 5(7.58) 1.71(0.59, 4.99) 0.325 0.530 17(8.25) 2.60(1.24, 5.45) 0.011 0.055
rs720012
 GG 64(19.39) 14(21.21) 1.00    45(21.84) 1.00   
 GA 154(46.67) 34(51.52) 1.00(0.51, 2.00) 0.979 0.979 115(55.83) 1.06(0.68, 1.67) 0.794 0.794
 AA 112(33.94) 18(27.27) 0.74(0.34, 1.58) 0.428 0.530 46(22.33) 0.58(0.35, 0.98) 0.040 0.067
rs720014
 TT 231(70.00) 50(75.76) 1.00    99(48.06) 1.00   
 TC 91(27.58) 13(19.70) 0.66(0.34, 1.27) 0.215 0.538 97(47.09) 2.49(1.72, 3.60) 1.40e-7 7.00e-07
 CC 8(2.42) 3(4.55) 1.73(0.44, 6.76) 0.429 0.530 10(4.85) 2.92(1.12, 7.61) 0.0287 0.067
rs9606241
 AA 240(72.73) 41(62.12) 1.00    139(67.48) 1.00   
 AG 83(25.15) 23(34.85) 1.62(0.92, 2.86) 0.095 0.475 60(29.13) 1.25(0.84, 1.85) 0.268 0.447
 GG 7(2.12) 2(3.03) 1.67(0.34, 8.33) 0.530 0.530 7(3.40) 1.27(0.59, 5.03) 0.316 0.395
  1. a FDR adjusted p value;
  2. Abbreviation: EOPE early onset preeclampsia, LOPE late onset preeclampsia