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Table 2 Minor allele frequencies among breast cancer patients and healthy controls and the HWEc P-value of CYP450 candidate gene polymorphisms

From: Association of CYP gene polymorphisms with breast cancer risk and prognostic factors in the Jordanian population

Gene SNP ID Cases (n = 221) Controls (n = 218)
MA MAFa HWEb p-value MA MAF HWE p-value
CYP19A1 rs7176005 T 0.23 0.85 T 0.15 0.18
rs6493497 A 0.22 0.56 A 0.15 0.18
rs700519 A 0.03 0.68 A 0.02 0.75
rs10046 A 0.42 0.27 A 0.44 0.50
rs4646 A 0.29 0.33 A 0.29 0.25
CYP2C9 rs1799853 T 0.14 0.084 T 0.15 0.063
rs4086116 T 0.22 0.17 T 0.23 0.036
CYP2C19 rs4244285 A 0.11 0.74 A 0.08 0.84
CYP1B1 rs10175368 T 0.29 0.87 T 0.26 0.16
CYP3A4 rs35599367 A 0.02 0.70 A 0.03 0.70
CYP1A2 rs762551 C 0.33 0.88 C 0.37 0.10
  1. MA minor allele
  2. N/A: not applicable
  3. aMAF: minor allele frequency
  4. bHWE: Hardy—Weinberg equilibrium