Association of CYP gene polymorphisms with breast cancer risk and prognostic factors in the Jordanian population

BMC Medical Genetics

Table 2 Minor allele frequencies among breast cancer patients and healthy controls and the HWEc P-value of CYP450 candidate gene polymorphisms

Gene	SNP ID	Cases (n = 221)			Controls (n = 218)
Gene	SNP ID	MA	MAF^a	HWE^b p-value	MA	MAF	HWE p-value
CYP19A1	rs7176005	T	0.23	0.85	T	0.15	0.18
	rs6493497	A	0.22	0.56	A	0.15	0.18
	rs700519	A	0.03	0.68	A	0.02	0.75
	rs10046	A	0.42	0.27	A	0.44	0.50
	rs4646	A	0.29	0.33	A	0.29	0.25
CYP2C9	rs1799853	T	0.14	0.084	T	0.15	0.063
CYP2C9	rs4086116	T	0.22	0.17	T	0.23	0.036
CYP2C19	rs4244285	A	0.11	0.74	A	0.08	0.84
CYP1B1	rs10175368	T	0.29	0.87	T	0.26	0.16
CYP3A4	rs35599367	A	0.02	0.70	A	0.03	0.70
CYP1A2	rs762551	C	0.33	0.88	C	0.37	0.10

ISSN: 1471-2350