A functional variant alters binding of activating protein 1 regulating expression of FGF7 gene associated with chronic obstructive pulmonary disease

Table 1 Description of study population

Variable		Controls	Cases	P
Variable		(n = 311)	(n = 258)	P
Age, years		63 ± 9	62 ± 8	NS
Sex(Male/Female)		277/34	230/28	NS
Smoking history	0–20 pack years	69	54	NS
Smoking history	20 pack years	242	204	NS
FEV1		1.81 ± 0.96	0.92 ± 0.45	< 0.05
FEV1 percentage of predicted, %		91.5 ± 4.8	44.1 ± 0.51	< 0.05
FEV1/FVC, %		76.2 ± 5.7	44.8 ± 9.4	< 0.05

FEV1 Forced Expiratory Volume in 1 s, NS not significant. Data are presented as mean ± SEM. FVC Forced Vital Capacity

ISSN: 1471-2350