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Table 4 Stratified analysis of the association of ATM polymorphisms with cancer under dominant model

From: ATM rs189037 (G > A) polymorphism increased the risk of cancer: an updated meta-analysis

Subgroup analysis Rs189037
n OR 95% CI p z I2(%) p h
Overall 15 1.207 1.090–1.337 < 0.001 40.9 0.050
Ethnicity
 East Asian 13 1.200 1.067–1.350 0.002 49.2 0.023
 Latino 1 1.254 1.007–1.563 0.043
 Caucasian 1 1.201 0.668–2.159 0.540
Source of controls
 Hospital-based 13 1.189 1.061–1.332 0.003 46.3 0.034
 Population-based 2 1.362 1.095–1.695 0.006 0.0 0.650
Type of cancer
 lung cancer 5 1.158 1.005–1.334 0.043 19.9 0.288
 breast cancer 2 1.341 1.035–1.737 0.026 43.3 0.184
 oral cancer 1 1.931 1.456–2.559 < 0.001
 leukemia 1 1.239 0.786–1.953 0.355
 thyroid carcinoma 4 1.094 0.897–1.335 0.374 20.3 0.288
 glioma 1 1.042 0.700–1.551 0.839
 colorectal cancer 1 1.153 0.931–1.429 0.192
  1. n, the number of studies; pz, p value for association test; ph, p value for heterogeneity test