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Table 2 Distribution of genotype and allele frequencies of the ATM rs189037 polymorphism

From: ATM rs189037 (G > A) polymorphism increased the risk of cancer: an updated meta-analysis

  Genotype distribution    Allele frequency  
Cases, n Controls, n   Cases, % Controls, %
Author GG GA AA GG GA AA P HWE G A G A
Kim 190 316 105 195 306 113 0.7130 56.96 43.04 56.68 43.32
Wang 428 580 224 474 567 191 0.3210 58.28 41.72 61.49 38.51
Bau 181 277 162 239 285 96 0.4704 51.53 48.47 61.53 38.47
Lo 238 345 145 239 354 124 0.7173 56.39 43.61 58.02 41.98
Wang 89 128 49 106 119 41 0.4295 57.52 42.48 62.22 37.78
Xu 375a 215 606a 277
Hsia 118 176 64 255 339 122 0.6068 57.54 42.46 59.29 40.71
Zhao 140 186 58 125 203 56 0.0697 60.68 39.32 58.98 41.02
Damiola 13 32 23 35 106 60 0.3121 42.65 57.35 43.78 56.22
Gu 90 196 69 102 189 69 0.2638 52.96 47.04 54.58 45.42
Liu 217 435 200 264 434 154 0.2927 51.00 49.00 56.46 43.54
Shen 148 240 99 152 272 92 0.1186 55.03 44.97 55.81 44.19
Song 134 211 83 56 84 42 0.3352 55.96 44.04 53.85 46.15
Yue 166 262 96 196 258 64 0.1371 56.68 43.32 62.74 37.26
Wang 336 543 227 362 491 191 0.2797 54.93 45.07 58.19 41.81
  1. Abbreviation: PHWE represents the P value of Hardy-Weinberg equilibrium test in the genotype distribution of controls
  2. arepresents the number of GG + GA