Table 3 Allele and genotypic frequencies of EREG SNPs in the PTB and controls
From: Polymorphism in the EREG gene confers susceptibility to tuberculosis
SNP | Allele/genotype | PTB (%) | HC (%) | P | OR[95%CI]a |
|---|---|---|---|---|---|
rs10518126 | C | 774 (91.3) | 1092 (91.0) | 0.83 | |
T | 74 (8.7) | 108 (9.0) | |||
C/C | 352 (83.0) | 492 (82.0) | 0.20 | ||
C/T | 70 (16.5) | 108 (18.0) | |||
T/T | 2 (0.5) | 0 (0.0) | |||
rs2367707 | A | 292 (34.4) | 312 (26.0) | 0.00019* | 1.49 (1.23-1.81) |
G | 556 (65.6) | 888 (74.0) | |||
A/A | 48 (11.3) | 48 (8.0) | 0.00051* | 1.86 (1.19-2.88) | |
A/G | 196 (46.2) | 216 (36.0) | |||
G/G | 180 (42.5) | 336 (56.0) | |||
rs3806794 | A | 88 (10.4) | 112 (9.3) | 0.43 | |
C | 760 (89.6) | 1088 (90.7) | |||
A/A | 6 (1.4) | 9 (1.5) | 0.63 | ||
A/C | 76 (17.9) | 94 (15.7) | |||
C/C | 342 (80.7) | 497 (82.8) | |||
rs6446993 | A | 364 (42.9) | 486 (40.5) | 0.27 | |
T | 484 (57.1) | 714 (59.5) | |||
A/A | 76 (17.9) | 108 (18.0) | 0.22 | ||
A/T | 212 (50.0) | 270 (45.0) | |||
T/T | 136 (32.1) | 222 (37.0) | |||
rs6836436 | G | 76 (9.0) | 126 (10.5) | 0.25 | |
T | 772 (91.0) | 1074 (89.5) | |||
G/G | 2 (0.5) | 6 (1.0) | 0.44 | ||
G/T | 72 (17.0) | 114 (19.0) | |||
T/T | 350 (82.5) | 480 (80.0) |