Fig. 5
From: Conservation analysis and pathogenicity prediction of mutant genes of ectodysplasin a
The pathogenicity prediction of the mutation site of c.878 T > G using the software PolyPhen-2. The mutation prediction is based on the results of second graph HumVar. The closer the score is to 0.00, the less possibility causing protein damage. The score of c.878 T > G was 0.997, which was close to 1.0, indicating that it theoretically had high pathogenicity and potentially caused damages