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Fig. 5 | BMC Medical Genetics

Fig. 5

From: Novel mutations in TPM2 and PIEZO2 are responsible for distal arthrogryposis (DA) 2B and mild DA in two Chinese families

Fig. 5

SWISS-MODEL prediction of the p.Q103R mutation in tropomyosin. a The 3-dimensional structure of wild-type tropomyosin with position 103 indicated by a black arrow. Nearby acidic (red) and basic (blue) surface properties are illustrated with the neutral glutamine residue shown as a yellow line. b Acidic surface properties are destroyed with the substitution of basic arginine for glutamine. The substitution is depicted as a blue line

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BMC Medical Genetics

ISSN: 1471-2350

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